| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Salt | $3,526,182 | - | 365 | - | $9,660 | $3,630,366 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Inception | $1,656,984 | -41.3% | 379 | -43 | $4,371 | $26,861,956 | 5 | Warner Bros. | false | false |
| 3 | 2 | The Expendables | $1,509,234 | -46.2% | 224 | - | $6,737 | $5,294,152 | 2 | Roadshow Films | false | false |
| 4 | 3 | Step Up 3D | $1,103,525 | -41.5% | 260 | -54 | $4,244 | $7,382,750 | 3 | Universal Pictures International (UPI) | false | false |
| 5 | 4 | Scott Pilgrim vs. the World | $564,100 | -33.1% | 177 | -1 | $3,187 | $1,779,371 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | 6 | The Ghost Writer | $296,538 | -44.2% | 76 | - | $3,901 | $1,222,385 | 2 | Hoyts Distribution | false | false |
| 7 | 5 | Killers | $233,082 | -59.8% | 214 | -32 | $1,089 | $4,812,739 | 4 | Roadshow Films | false | false |
| 8 | - | Matching Jack | $230,886 | - | 186 | - | $1,241 | $245,941 | 1 | 20th Century Fox International | true | false |
| 9 | - | Toy Story 3 | $150,643 | - | 80 | - | $1,883 | $37,599,293 | - | Walt Disney Pictures | - | false |
| 10 | 9 | The Twilight Saga: Eclipse | $93,879 | -51% | 92 | -60 | $1,020 | $28,566,737 | 8 | - | false | false |
| 11 | 8 | Knight and Day 2010 Re-release | $82,058 | -70.4% | 100 | -66 | $820 | $8,958,470 | 6 | 20th Century Fox International | false | false |
| 12 | 13 | Hubble | $55,231 | -14.9% | 5 | - | $11,046 | $170,561 | 15 | IMAX | false | false |
| 13 | - | Four Lions | $50,354 | - | 11 | - | $4,577 | $95,018 | 1 | Hopscotch Films | true | false |
| 14 | - | Cairo Time | $48,338 | - | 12 | - | $4,028 | $66,696 | 1 | Paramount Pictures International | true | false |
| 15 | 11 | The Special Relationship | $40,785 | -62.8% | 51 | -1 | $799 | $444,762 | 3 | Roadshow Films | false | false |
| 16 | 10 | The Karate Kid | $39,854 | -72.6% | 80 | -83 | $498 | $11,913,479 | 7 | Sony Pictures Releasing | false | false |
| 17 | 12 | Me and Orson Welles | $33,191 | -50.6% | 29 | +1 | $1,144 | $395,211 | 4 | Madman Entertainment | false | false |
| 18 | 14 | South Solitary | $30,742 | -50.9% | 34 | -10 | $904 | $421,658 | 4 | Icon Film Distribution | false | false |
| 19 | - | Father of My Children | $20,902 | - | 14 | - | $1,493 | $52,496 | - | Palace Films | - | false |
| 20 | 15 | Splice 2010 Re-release | $20,842 | -61.3% | 36 | -2 | $578 | $103,702 | 2 | Madman Entertainment | false | false |
| 21 | - | Lafangey Parindey | $18,686 | - | 8 | - | $2,335 | $18,686 | 1 | Mind Blowing Films | true | false |
| 22 | - | 4.3.2.1. | $8,018 | - | 42 | - | $190 | $8,018 | 1 | Universal Pictures International (UPI) | true | false |
