| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Step Up 3D | $507,397 | -26% | 66 | -2 | $7,687 | $1,412,042 | 2 | Belga Films | false | false |
| 2 | 2 | Inception | $494,325 | -19.7% | 92 | - | $5,373 | $3,510,225 | 4 | Warner Bros. | false | false |
| 3 | - | The Sorcerer's Apprentice | $489,255 | - | 58 | - | $8,435 | $491,382 | 1 | Walt Disney Pictures | true | false |
| 4 | 10 | A Turtle's Tale: Sammy's Adventures | $359,505 | +79.1% | 62 | +32 | $5,798 | $608,203 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 5 | 3 | The Last Airbender | $325,320 | -40.3% | 57 | -1 | $5,707 | $2,252,183 | 3 | Universal Pictures International (UPI) | false | false |
| 6 | 5 | Knight and Day 2010 Re-release | $284,644 | -36% | 85 | - | $3,348 | $1,692,595 | 3 | 20th Century Fox International | false | false |
| 7 | 4 | Salt | $284,134 | -38.1% | 46 | - | $6,176 | $856,076 | 2 | Sony Pictures Releasing | false | false |
| 8 | 7 | Cats & Dogs: The Revenge of Kitty Galore | $278,188 | -13.3% | 71 | - | $3,918 | $706,043 | 2 | Warner Bros. | false | false |
| 9 | 8 | Toy Story 3 | $248,195 | -19.9% | 84 | -18 | $2,954 | $4,381,687 | 8 | Walt Disney Pictures | false | false |
| 10 | 6 | Shrek Forever After | $233,631 | -33.7% | 98 | -18 | $2,383 | $4,000,288 | 5 | Universal Pictures International (UPI) | false | false |
| 11 | 9 | The Karate Kid | $176,947 | -34.5% | 56 | -4 | $3,159 | $1,901,560 | 4 | Sony Pictures Releasing | false | false |
| 12 | 11 | The Twilight Saga: Eclipse | $116,253 | -39.1% | 58 | -28 | $2,004 | $6,170,507 | 7 | Belga Films | false | false |
| 13 | - | Hot Tub Time Machine | $75,257 | - | 25 | - | $3,010 | $75,257 | 1 | 20th Century Fox International | true | false |
| 14 | - | Copacabana Palace 2010 Re-release | $49,545 | - | 11 | - | $4,504 | $58,533 | 1 | Cinéart | true | false |
| 15 | 13 | Killers | $43,232 | -17% | 11 | -10 | $3,930 | $954,622 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 16 | 12 | With Love... from the Age of Reason | $37,633 | -32% | 13 | - | $2,894 | $122,099 | 2 | Cinéart | false | false |
| 17 | 14 | The Italian | $24,426 | -35.6% | 9 | -2 | $2,714 | $302,761 | 5 | Alternative Films | false | false |
| 18 | 15 | Predators | $16,849 | -49.3% | 13 | -15 | $1,296 | $690,497 | 5 | 20th Century Fox International | false | false |
| 19 | 18 | Sex and the City 2 | $16,269 | +2% | 11 | - | $1,479 | $2,701,791 | 11 | Warner Bros. | false | false |
| 20 | 16 | Furry Vengeance | $15,389 | -29.6% | 11 | -4 | $1,399 | $161,401 | 4 | Belga Films | false | false |
| 21 | 23 | The Back-up Plan | $7,857 | +26.5% | 1 | -4 | $7,857 | $361,505 | 8 | Sony Pictures Releasing | false | false |
| 22 | - | Come Undone | $7,540 | - | 6 | - | $1,256 | $7,654 | 1 | ABC Distribution | true | false |
| 23 | 19 | My Afternoons with Margueritte | $6,253 | -44.8% | 10 | -2 | $625 | $209,173 | 8 | Cinéart | false | false |
| 24 | 28 | Wandering Streams | $5,203 | +65.6% | 7 | +4 | $743 | $27,368 | 5 | N/A | false | false |
| 25 | 31 | The Last Station 2010 Re-release | $5,005 | +96.4% | 4 | - | $1,251 | $36,437 | 9 | Belga Films | false | false |
| 26 | 17 | The Fourth Kind | $4,997 | -73.9% | 6 | -6 | $832 | $85,599 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 27 | 20 | Splice 2010 Re-release | $4,534 | -46.5% | 12 | - | $377 | $83,962 | 3 | Benelux Film Distributors | false | false |
| 28 | 21 | Babies | $4,441 | -46.1% | 4 | -3 | $1,110 | $47,766 | 4 | Cinéart | false | false |
| 29 | 26 | Horn of Plenty 2010 Re-release | $2,812 | -40.5% | 3 | +1 | $937 | $16,500 | 3 | N/A | false | false |
| 30 | 29 | Law Abiding Citizen | $2,769 | -3.4% | 1 | -1 | $2,769 | $462,774 | 11 | Belga Films | false | false |
| 31 | 25 | Me Too | $2,615 | -49.7% | 4 | - | $653 | $23,372 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 32 | 27 | Baaria | $2,571 | -19.2% | 6 | -1 | $428 | $44,947 | 7 | Paradiso Entertainment | false | false |
| 33 | - | L'Ours Et Le Magicien | $1,758 | - | 4 | - | $439 | $1,758 | 1 | N/A | true | false |
| 34 | 35 | The Ghost Writer | $1,691 | +21.7% | 2 | - | $845 | $867,115 | 21 | Benelux Film Distributors | false | false |
| 35 | 32 | The Illusionist | $1,496 | -27.3% | 3 | -1 | $498 | $51,464 | 9 | Paradiso Entertainment | false | false |
| 36 | 38 | Alamar | $747 | +22.9% | 4 | - | $186 | $15,829 | 6 | Benelux Film Distributors | false | false |
| 37 | 39 | Agora | $368 | +24.7% | 2 | - | $184 | $168,293 | 17 | Benelux Film Distributors | false | false |
| 38 | 36 | Chicas | $353 | -67.5% | 3 | - | $117 | $7,894 | 5 | Benelux Film Distributors | false | false |
