| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Salt | $20,411 | - | 7 | - | $2,915 | $20,411 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Inception | $8,189 | -44.5% | 6 | - | $1,364 | $80,830 | 3 | Warner Bros. | false | false |
| 3 | - | Cats & Dogs: The Revenge of Kitty Galore | $5,110 | - | 9 | - | $567 | $6,775 | 1 | Warner Bros. | true | false |
| 4 | 2 | Knight and Day 2010 Re-release | $4,043 | -53.9% | 7 | - | $577 | $24,548 | 2 | 20th Century Fox International | false | false |
| 5 | 4 | Killers | $3,976 | +2.2% | 3 | - | $1,325 | $54,629 | 5 | N/A | false | false |
| 6 | 3 | Sex and the City 2 | $3,332 | -42.4% | 9 | - | $370 | $354,252 | 10 | Warner Bros. | false | false |
| 7 | 5 | Shrek Forever After | $2,341 | -36.4% | 7 | - | $334 | $148,967 | 11 | United International Pictures | false | false |
| 8 | 6 | The Sorcerer's Apprentice | $2,057 | -42.3% | 4 | - | $514 | $42,572 | 4 | United International Pictures | false | false |
| 9 | 11 | When You're Strange | $1,783 | -5.4% | 1 | - | $1,783 | $5,536 | 2 | N/A | false | false |
| 10 | 8 | Prince of Persia: The Sands of Time | $1,754 | -32.7% | 6 | - | $292 | $147,419 | 10 | Walt Disney Pictures | false | false |
| 11 | 10 | The Twilight Saga: Eclipse | $1,522 | -29.1% | 5 | - | $304 | $84,101 | 6 | N/A | false | false |
| 12 | 13 | A Nightmare on Elm Street | $980 | -18.1% | 6 | - | $163 | $53,574 | 8 | Warner Bros. | false | false |
| 13 | 7 | Toy Story 3 | $975 | -65.4% | 7 | - | $139 | $63,599 | 8 | Walt Disney Pictures | false | false |
| 14 | 12 | The Back-up Plan | $918 | -42.5% | 5 | -2 | $183 | $55,488 | 8 | Sony Pictures Releasing | false | false |
| 15 | 9 | Get Him to the Greek | $434 | -79.9% | 4 | - | $108 | $12,747 | 3 | United International Pictures | false | false |
| 16 | 14 | Robin Hood | $152 | -82.6% | 7 | - | $21 | $161,124 | 13 | United International Pictures | false | false |
| 17 | 15 | The A-Team | $115 | -76.2% | 6 | - | $19 | $10,082 | 5 | 20th Century Fox International | false | false |
| 18 | 18 | Date Night | $41 | -56.4% | 7 | - | $5 | $26,714 | 12 | 20th Century Fox International | false | false |
| 19 | 19 | Paintball | $6 | - | 1 | - | $6 | $5,447 | 7 | N/A | false | false |
