| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Sorcerer's Apprentice | $517,281 | - | 88 | - | $5,878 | $517,281 | 1 | Walt Disney Pictures | true | false |
| 2 | - | Inception | $330,977 | - | 52 | - | $6,364 | $330,977 | 1 | Warner Bros. | true | false |
| 3 | 1 | Despicable Me | $203,197 | -42.9% | 73 | +1 | $2,783 | $729,862 | 2 | Universal Pictures International (UPI) | false | false |
| 4 | 3 | The Twilight Saga: Eclipse | $109,441 | -52.1% | 94 | -3 | $1,164 | $1,546,826 | 3 | N/A | false | false |
| 5 | 2 | The Last Airbender | $99,032 | -63.9% | 78 | -1 | $1,269 | $1,555,902 | 3 | Paramount Pictures International | false | false |
| 6 | 4 | Predators | $23,989 | -71.6% | 47 | -3 | $510 | $337,123 | 3 | 20th Century Fox International | false | false |
| 7 | 6 | Toy Story 3 | $3,702 | -73.9% | 33 | -18 | $112 | $650,491 | 5 | Walt Disney Pictures | false | false |
| 8 | 5 | Knight and Day 2010 Re-release | $3,431 | -78.8% | 23 | -23 | $149 | $589,420 | 5 | 20th Century Fox International | false | false |
| 9 | - | Bitch Slap | $2,361 | - | 7 | - | $337 | $2,361 | 1 | N/A | true | false |
| 10 | 7 | Avatar | $1,571 | -85.8% | 3 | +1 | $523 | $8,181,957 | 32 | 20th Century Fox International | false | false |
| 11 | 8 | The Alien Girl | $600 | -91.3% | 11 | -16 | $54 | $114,609 | 4 | N/A | false | false |
| 12 | 14 | Cop Out | $511 | -63.2% | 5 | - | $102 | $157,545 | 6 | Warner Bros. | false | false |
| 13 | 13 | Sex and the City 2 | $490 | -68.8% | 5 | - | $98 | $918,647 | 8 | Warner Bros. | false | false |
| 14 | 15 | The A-Team | $421 | - | 4 | -3 | $105 | $227,976 | 7 | 20th Century Fox International | false | false |
| 15 | 11 | Prince of Persia: The Sands of Time | $182 | -91.2% | 8 | -22 | $22 | $1,574,955 | 8 | Walt Disney Pictures | false | false |
| 16 | 9 | Shrek Forever After | $106 | -97.6% | 1 | -10 | $106 | $3,998,707 | 10 | Paramount Pictures International | false | false |
| 17 | 12 | Get Him to the Greek | $47 | -97.2% | 1 | -5 | $47 | $157,738 | 6 | Universal Pictures International (UPI) | false | false |
