| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Shrek Forever After | $454,528 | - | 226 | - | $2,011 | $879,811 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | The Twilight Saga: Eclipse | $370,225 | -55.1% | 105 | - | $3,525 | $2,151,449 | 2 | Independent Films | false | false |
| 3 | 2 | Toy Story 3 | $226,431 | -34.8% | 188 | +4 | $1,204 | $1,528,083 | 3 | Walt Disney Pictures | false | false |
| 4 | 3 | Sex and the City 2 | $81,747 | -35.2% | 114 | -5 | $717 | $4,600,247 | 7 | Warner Bros. | false | false |
| 5 | - | Unthinkable | $61,958 | - | 26 | - | $2,383 | $97,344 | 1 | A-Film Distribution | true | false |
| 6 | 5 | Get Him to the Greek | $60,226 | -35.6% | 39 | - | $1,544 | $218,925 | 2 | Universal Pictures International (UPI) | false | false |
| 7 | 4 | The A-Team | $59,775 | -40.2% | 91 | -3 | $656 | $1,375,469 | 5 | Warner Bros. | false | false |
| 8 | 6 | Killers | $44,467 | -33.2% | 60 | +2 | $741 | $1,099,248 | 6 | A-Film Distribution | false | false |
| 9 | 9 | Letters to Juliet | $31,772 | -33.1% | 55 | +1 | $577 | $469,651 | 4 | Entertainment One | false | false |
| 10 | 7 | The Back-up Plan | $31,488 | -43.6% | 38 | -5 | $828 | $512,850 | 4 | Sony Pictures Releasing | false | false |
| 11 | 8 | Prince of Persia: The Sands of Time | $28,640 | -44.9% | 50 | -17 | $572 | $2,403,661 | 8 | Walt Disney Pictures | false | false |
| 12 | - | Leap Year | $21,048 | - | 10 | - | $2,104 | $41,911 | 1 | Universal Pictures International (UPI) | true | false |
| 13 | 10 | Robin Hood | $18,597 | -46.5% | 34 | -27 | $546 | $3,512,165 | 9 | Universal Pictures International (UPI) | false | false |
| 14 | - | Greenberg | $10,220 | - | 6 | - | $1,703 | $13,457 | 1 | Benelux Film Distributors | true | false |
| 15 | 12 | The Ghost Writer | $6,500 | -33.5% | 16 | -3 | $406 | $496,965 | 8 | Benelux Film Distributors | false | false |
| 16 | 13 | Mao's Last Dancer | $4,943 | -40.6% | 14 | - | $353 | $68,931 | 4 | Wild Bunch Distribution | false | false |
| 17 | 16 | Me Too | $4,904 | -24.6% | 13 | - | $377 | $273,330 | 9 | A-Film Distribution | false | false |
| 18 | 14 | StreetDance 2 | $3,133 | -59.3% | 5 | -6 | $626 | $793,579 | 8 | Entertainment One | false | false |
| 19 | 11 | She's Out of My League | $2,980 | -70.7% | 11 | -10 | $270 | $439,743 | 6 | Universal Pictures International (UPI) | false | false |
| 20 | 17 | Agora | $2,850 | -51.3% | 10 | -1 | $285 | $103,281 | 6 | Benelux Film Distributors | false | false |
| 21 | - | The Good Heart | $660 | - | 3 | - | $220 | $660 | 1 | Wild Bunch Distribution | true | false |
