| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The A-Team | $396,533 | -64.3% | - | - | - | $2,001,635 | 2 | 20th Century Fox International | false | false |
| 2 | 2 | The Hole | $213,197 | -60.6% | - | - | - | $1,850,677 | 3 | Medusa Distribuzione | false | false |
| 3 | - | Cop Out | $190,847 | - | - | - | - | $190,847 | 1 | Warner Bros. | true | false |
| 4 | 6 | Prince of Persia: The Sands of Time | $142,823 | -60.2% | - | - | - | $8,013,138 | 6 | Walt Disney Pictures | false | false |
| 5 | 3 | I Hate Valentine's Day | $141,661 | -64% | - | - | - | $693,990 | 2 | Eagle Pictures | false | false |
| 6 | 5 | Nanny McPhee Returns | $111,313 | -69.2% | - | - | - | $1,541,604 | 4 | United International Pictures | false | false |
| 7 | 4 | Sex and the City 2 | $107,409 | -70.3% | - | - | - | $7,530,700 | 5 | Warner Bros. | false | false |
| 8 | 7 | Robin Hood | $84,543 | -63.3% | - | - | - | $13,582,186 | 7 | United International Pictures | false | false |
| 9 | 10 | Bright Star | $79,538 | -54.9% | - | - | - | $585,391 | 3 | 01 Distribution | false | false |
| 10 | 11 | The Secret in Their Eyes | $78,871 | -54.9% | - | - | - | $769,360 | 4 | Lucky Red | false | false |
| 11 | 16 | L'imbroglio nel lenzuolo | $66,619 | -31.8% | - | - | - | $231,049 | 2 | 01 Distribution | false | false |
| 12 | 8 | Saw VI | $64,375 | -70.1% | - | - | - | $2,254,462 | 4 | 01 Distribution | false | false |
| 13 | 9 | La nostra vita | $63,273 | -64.7% | - | - | - | $3,940,294 | 6 | 01 Distribution | false | false |
| 14 | 12 | Pope Joan | $62,029 | -56% | - | - | - | $822,049 | 4 | Medusa Distribuzione | false | false |
| 15 | - | City Island | $52,643 | - | - | - | - | $52,643 | 1 | Mikado Film | true | false |
| 16 | 13 | She's Out of My League | $50,719 | -61.2% | - | - | - | $234,721 | 2 | United International Pictures | false | false |
| 17 | 14 | The Road | $46,320 | -63.9% | - | - | - | $1,438,520 | 5 | N/A | false | false |
| 18 | 15 | Tooth Fairy | $35,204 | -68.8% | - | - | - | $378,830 | 3 | 20th Century Fox International | false | false |
| 19 | 17 | The Final Destination | $30,925 | -65% | - | - | - | $4,514,261 | 6 | Warner Bros. | false | false |
| 20 | - | The Maid | $22,508 | - | - | - | - | $22,508 | 1 | N/A | true | false |
| 21 | 22 | About Elly | $20,660 | -29.2% | 23 | +10 | $898 | $62,066 | 2 | N/A | false | false |
| 22 | 18 | Remembering the Children | $18,112 | -60.2% | 22 | - | $823 | $134,559 | 3 | Teodora Film | false | false |
| 23 | 23 | Basilicata Coast to Coast | $15,892 | -27.4% | 18 | +3 | $882 | $3,565,991 | 12 | Eagle Pictures | false | false |
| 24 | 19 | The Time That Remains | $12,250 | -64.7% | 17 | - | $720 | $164,385 | 4 | BIM Distribuzione | false | false |
| 25 | - | Draquila - L'Italia che trema | $10,735 | - | 28 | - | $383 | $2,059,068 | 8 | BIM Distribuzione | false | false |
| 26 | 25 | The Ghost Writer | $10,042 | -16.4% | 9 | +2 | $1,115 | $4,366,235 | 12 | 01 Distribution | false | false |
| 27 | 20 | The Girl Who Kicked the Hornet's Nest | $8,469 | -75.5% | 24 | - | $352 | $818,396 | 5 | BIM Distribuzione | false | false |
| 28 | - | Avatar | $8,110 | - | 16 | - | $506 | $80,191,374 | 24 | 20th Century Fox International | false | false |
| 29 | - | All About Steve | $7,783 | - | 10 | - | $778 | $7,783 | 1 | 20th Century Fox International | true | false |
| 30 | 21 | The Back-up Plan | $6,170 | -79.9% | 18 | -5 | $342 | $1,923,260 | 7 | Sony Pictures Releasing | false | false |
| 31 | 26 | Departures | $5,353 | -54.1% | 5 | -2 | $1,070 | $706,440 | 12 | N/A | false | false |
| 32 | 27 | The Last Station 2010 Re-release | $5,320 | -42.7% | 19 | +2 | $280 | $121,077 | 5 | Sony Pictures Releasing | false | false |
