| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Iron Man 2 | $236,187 | -43.5% | 95 | +1 | $2,486 | $916,809 | 2 | United International Pictures | false | false |
| 2 | 2 | Clash of the Titans | $172,992 | -46% | 82 | +2 | $2,109 | $2,441,497 | 4 | Warner Bros. | false | false |
| 3 | - | Legion | $100,996 | - | 41 | - | $2,463 | $100,996 | 1 | Sony Pictures Releasing | true | false |
| 4 | 3 | Date Night | $66,240 | -37.2% | 42 | -2 | $1,577 | $1,040,067 | 5 | 20th Century Fox International | false | false |
| 5 | 4 | Paranormal Activity | $31,328 | -57% | 33 | -3 | $949 | $274,692 | 3 | N/A | false | false |
| 6 | - | Bad Lieutenant: Port of Call New Orleans | $30,907 | - | 23 | - | $1,343 | $30,907 | 1 | N/A | true | false |
| 7 | 5 | How to Train Your Dragon | $22,601 | -55.8% | 45 | - | $502 | $1,641,279 | 7 | United International Pictures | false | false |
| 8 | 7 | Dear John | $12,181 | -51.4% | 15 | - | $812 | $101,341 | 3 | Sony Pictures Releasing | false | false |
| 9 | 6 | Alice in Wonderland | $10,420 | -62.7% | 25 | -6 | $416 | $4,303,875 | 10 | Walt Disney Pictures | false | false |
| 10 | 13 | I Hate Valentine's Day | $8,449 | -6% | 10 | - | $844 | $103,410 | 4 | N/A | false | false |
| 11 | 8 | Did You Hear About the Morgans? | $7,701 | -62.1% | 11 | -10 | $700 | $248,983 | 4 | Sony Pictures Releasing | false | false |
| 12 | 9 | Case 39 | $6,757 | -61.7% | 13 | -2 | $519 | $249,870 | 5 | United International Pictures | false | false |
| 13 | 15 | A Prophet | $5,650 | -36.8% | 3 | - | $1,883 | $25,827 | 2 | Sony Pictures Releasing | false | false |
| 14 | 11 | The Imaginarium of Doctor Parnassus | $5,258 | -57.3% | 6 | -4 | $876 | $91,193 | 4 | Sony Pictures Releasing | false | false |
| 15 | 14 | Everybody's Fine | $5,203 | -42% | 10 | +3 | $520 | $96,840 | 5 | Walt Disney Pictures | false | false |
| 16 | 12 | The Book of Eli | $3,784 | -62.2% | 7 | -2 | $540 | $996,734 | 7 | Sony Pictures Releasing | false | false |
| 17 | 10 | The Bounty Hunter | $3,719 | -74.4% | 8 | -7 | $464 | $660,978 | 6 | Sony Pictures Releasing | false | false |
| 18 | 18 | 500 Days of Summer | $1,592 | +2.1% | 5 | +3 | $318 | $93,114 | 7 | 20th Century Fox International | false | false |
| 19 | 16 | Street Fighter: The Legend of Chun-Li | $1,494 | -58% | 5 | -7 | $298 | $32,663 | 3 | N/A | false | false |
| 20 | 22 | Feast 2010 Re-release | $1,177 | +243.1% | 3 | +2 | $392 | $27,423 | 8 | N/A | false | false |
| 21 | 21 | The Return 2010 Re-release | $1,177 | +187.8% | 1 | - | $1,177 | $121,152 | 11 | N/A | false | false |
| 22 | 17 | The Haunting in Connecticut | $1,133 | -65.2% | 3 | -1 | $377 | $268,002 | 7 | N/A | false | false |
| 23 | 19 | Couples Retreat | $749 | -34.8% | 2 | - | $374 | $369,687 | 7 | United International Pictures | false | false |
