| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Iron Man 2 | $536,356 | -28.9% | 82 | -1 | $6,540 | $1,510,085 | 2 | Paramount Pictures International | false | false |
| 2 | - | Carancho | $418,554 | - | 64 | - | $6,539 | $418,554 | 1 | Walt Disney Pictures | true | false |
| 3 | 2 | Clash of the Titans | $352,855 | -13.1% | 114 | +8 | $3,095 | $3,413,413 | 4 | Warner Bros. | false | false |
| 4 | - | A Nightmare on Elm Street | $312,388 | - | 48 | - | $6,508 | $312,388 | 1 | Warner Bros. | true | false |
| 5 | 4 | Alice in Wonderland | $86,085 | +3.8% | 71 | -18 | $1,212 | $8,043,120 | 10 | Walt Disney Pictures | false | false |
| 6 | - | From Paris with Love | $79,840 | - | 44 | - | $1,814 | $79,840 | 1 | N/A | true | false |
| 7 | 3 | Brother and Sister | $72,217 | -24.9% | 67 | -2 | $1,077 | $1,729,721 | 6 | Primer Plano Film Group | false | false |
| 8 | 5 | How to Train Your Dragon | $54,151 | -10.6% | 56 | -34 | $966 | $1,745,400 | 7 | Paramount Pictures International | false | false |
| 9 | 6 | The Men Who Stare at Goats | $23,709 | -39.1% | 26 | -4 | $911 | $165,455 | 3 | Sony Pictures Releasing | false | false |
| 10 | 8 | Shutter Island | $21,577 | -33.1% | 36 | -4 | $599 | $1,560,618 | 9 | Paramount Pictures International | false | false |
| 11 | 9 | Remember Me | $20,491 | -26.1% | 19 | -8 | $1,078 | $260,644 | 5 | Alfa Films | false | false |
| 12 | 7 | The White Ribbon | $19,801 | -38.8% | 14 | -1 | $1,414 | $134,293 | 3 | N/A | false | false |
| 13 | 17 | The Beaches of Agnès | $19,330 | +46.1% | 8 | +2 | $2,416 | $37,095 | 2 | IFA | false | false |
| 14 | 12 | Date Night | $16,027 | -17.2% | 26 | -4 | $616 | $358,033 | 5 | 20th Century Fox International | false | false |
| 15 | - | Me Two 2010 Re-release | $12,919 | - | 15 | - | $861 | $12,919 | 1 | Distribution Company | true | false |
| 16 | 18 | Avatar | $11,118 | +0.7% | 4 | +1 | $2,779 | $13,442,324 | 19 | 20th Century Fox International | false | false |
| 17 | 14 | Case 39 | $9,735 | -45.8% | 14 | -15 | $695 | $257,613 | 5 | Paramount Pictures International | false | false |
| 18 | 16 | Love Happens | $9,483 | -29.7% | 18 | -11 | $526 | $163,138 | 4 | Distribution Company | false | false |
| 19 | 11 | It's Alive | $9,028 | -58.6% | 11 | -10 | $820 | $90,904 | 3 | Distribution Company | false | false |
| 20 | 10 | A Single Man | $8,828 | -59.5% | 12 | -1 | $735 | $91,203 | 3 | N/A | false | false |
| 21 | 13 | Synecdoche, New York | $5,737 | -69.4% | 10 | - | $573 | $30,003 | 2 | Distribution Company | false | false |
| 22 | 19 | The Fourth Kind | $5,609 | -22.5% | 8 | -4 | $701 | $170,967 | 6 | Alfa Films | false | false |
| 23 | 21 | The Box | $5,438 | +19.8% | 6 | -3 | $906 | $1,356,490 | 4 | Alfa Films | false | false |
| 24 | 22 | The Blind Side | $5,345 | +23.3% | 10 | -12 | $534 | $306,499 | 8 | Warner Bros. | false | false |
| 25 | 20 | Seraphine | $4,885 | -17.2% | 10 | +3 | $488 | $106,119 | 6 | N/A | false | false |
| 26 | 15 | Ex | $2,829 | -84.1% | 5 | -11 | $565 | $68,656 | 3 | Primer Plano Film Group | false | false |
| 27 | 26 | The Book of Eli | $1,824 | -47.4% | 7 | -11 | $260 | $588,113 | 8 | Sony Pictures Releasing | false | false |
| 28 | 24 | The Bounty Hunter | $1,255 | -65.5% | 5 | -7 | $251 | $330,072 | 6 | Sony Pictures Releasing | false | false |
| 29 | - | Dilettante | $1,131 | - | 1 | - | $1,131 | $1,131 | 1 | Primer Plano Film Group | true | false |
| 30 | 42 | Crazy Heart | $1,032 | +454.8% | 4 | +3 | $258 | $108,473 | 9 | 20th Century Fox International | false | false |
| 31 | 27 | The Rebound | $974 | -66.1% | 3 | -4 | $324 | $124,134 | 7 | Alfa Films | false | false |
| 32 | 25 | Couples Retreat | $792 | -77.9% | 2 | -1 | $396 | $167,416 | 10 | Universal Pictures International (UPI) | false | false |
| 33 | 29 | Everybody's Fine | $550 | -77.1% | 1 | -7 | $550 | $189,811 | 8 | Walt Disney Pictures | false | false |
| 34 | 32 | Precious | $488 | -56.7% | 1 | -3 | $488 | $302,678 | 13 | N/A | false | false |
| 35 | 40 | Astro Boy | $394 | +70.6% | 1 | - | $394 | $174,796 | 15 | Alfa Films | false | false |
| 36 | 34 | Paco | $337 | -40% | 4 | -1 | $84 | $182,575 | 8 | Primer Plano Film Group | false | false |
| 37 | 28 | Remembering the Children | $273 | -90% | 3 | -5 | $91 | $56,567 | 5 | Distribution Company | false | false |
| 38 | 31 | Dear John | $263 | -87.2% | 1 | -6 | $263 | $68,860 | 4 | Sony Pictures Releasing | false | false |
| 39 | 33 | Did You Hear About the Morgans? | $259 | -58.6% | 1 | -1 | $259 | $283,813 | 9 | Sony Pictures Releasing | false | false |
| 40 | 36 | Alvin and the Chipmunks: The Squeakquel | $193 | -58.5% | 1 | - | $193 | $1,089,254 | 16 | 20th Century Fox International | false | false |
| 41 | 30 | Edge of Darkness | $78 | -96.7% | 1 | -4 | $78 | $1,141,602 | 11 | Warner Bros. | false | false |
| 42 | 44 | 9 | $46 | +4.5% | 1 | - | $46 | $38,881 | 8 | Distribution Company | false | false |
| 43 | 46 | Old Dogs | $32 | +77.8% | 1 | - | $32 | $1,506,322 | 16 | Walt Disney Pictures | false | false |
| 44 | 23 | Ricky | $18 | -99.6% | 1 | -7 | $18 | $5,453 | 2 | Impacto Cine | false | false |
