| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Clash of the Titans | $278,454 | -38.5% | 83 | - | $3,354 | $860,501 | 2 | Warner Bros. | false | false |
| 2 | 4 | How to Train Your Dragon | $101,515 | -5.1% | 68 | -5 | $1,492 | $1,963,715 | 5 | United International Pictures | false | false |
| 3 | 3 | Date Night | $100,344 | -10.5% | 59 | - | $1,700 | $514,878 | 3 | 20th Century Fox International | false | false |
| 4 | 2 | The Bounty Hunter | $98,322 | -12.4% | 56 | -1 | $1,755 | $1,201,098 | 4 | Sony Pictures Releasing | false | false |
| 5 | - | When in Rome | $91,545 | - | 30 | - | $3,051 | $91,545 | 1 | Walt Disney Pictures | true | false |
| 6 | - | Jakhalsdans | $79,732 | - | 40 | - | $1,993 | $79,732 | 1 | N/A | true | false |
| 7 | 5 | Leap Year | $52,825 | -27% | 44 | +4 | $1,200 | $170,151 | 2 | United International Pictures | false | false |
| 8 | - | Kick-Ass | $50,642 | - | 40 | - | $1,266 | $50,642 | 1 | NuMetro Distribution | true | false |
| 9 | 6 | Tooth Fairy | $42,073 | -23.3% | 47 | -15 | $895 | $1,424,901 | 6 | 20th Century Fox International | false | false |
| 10 | 9 | Hachi: A Dog's Tale | $40,970 | -13% | 24 | - | $1,707 | $104,610 | 2 | Ster-Kinekor Pictures | false | false |
| 11 | 7 | Nanny McPhee Returns | $39,782 | -20.3% | 35 | -5 | $1,136 | $439,946 | 4 | United International Pictures | false | false |
| 12 | 8 | The Blind Side | $36,449 | -23.8% | 48 | - | $759 | $980,253 | 6 | Warner Bros. | false | false |
| 13 | - | The Accidental Husband | $33,943 | - | 20 | - | $1,697 | $33,943 | 1 | Ster-Kinekor Pictures | true | false |
| 14 | 10 | Alice in Wonderland | $22,487 | -45.2% | 24 | -25 | $936 | $3,106,388 | 8 | Walt Disney Pictures | false | false |
| 15 | - | Extraordinary Measures | $19,527 | - | 16 | - | $1,220 | $19,527 | 1 | Sony Pictures Releasing | true | false |
| 16 | 11 | The Hurt Locker | $11,580 | -43.1% | 13 | -6 | $890 | $295,254 | 5 | NuMetro Distribution | false | false |
| 17 | 12 | It's Complicated | $9,965 | -49.6% | 20 | -8 | $498 | $1,553,559 | 9 | United International Pictures | false | false |
| 18 | 14 | The Last Station 2010 Re-release | $9,662 | -1.8% | 9 | - | $1,073 | $98,627 | 5 | Ster-Kinekor Pictures | false | false |
| 19 | 13 | Shutter Island | $8,451 | -36.4% | 18 | -4 | $469 | $730,381 | 7 | United International Pictures | false | false |
| 20 | 17 | Nine | $5,182 | -8.4% | 6 | - | $863 | $195,627 | 7 | Sony Pictures Releasing | false | false |
| 21 | 19 | The Spy Next Door 2010 Re-release | $4,147 | -19.1% | 6 | -3 | $691 | $648,495 | 12 | N/A | false | false |
| 22 | 16 | Outrageous | $1,493 | -74.3% | 1 | -10 | $1,493 | $26,069 | 3 | N/A | false | false |
| 23 | - | The Wolfman | $871 | - | 2 | - | $435 | $535,525 | 11 | N/A | false | false |
