| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Alice in Wonderland | $629,981 | -14.5% | 105 | -13 | $5,999 | $4,600,934 | 4 | Walt Disney Pictures | false | false |
| 2 | - | How to Train Your Dragon | $607,469 | - | 110 | - | $5,522 | $824,797 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | - | The Bounty Hunter | $261,546 | - | 30 | - | $8,718 | $261,546 | 1 | Sony Pictures Releasing | true | false |
| 4 | 2 | Shutter Island | $161,725 | -20% | 42 | -4 | $3,850 | $2,794,430 | 6 | Universal Pictures International (UPI) | false | false |
| 5 | 3 | The Ghost Writer | $140,801 | -26.1% | 34 | - | $4,141 | $422,061 | 2 | Benelux Film Distributors | false | false |
| 6 | - | Bad Lieutenant: Port of Call New Orleans | $131,917 | - | 32 | - | $4,122 | $162,107 | 1 | Benelux Film Distributors | true | false |
| 7 | 5 | Wolf 2010 Re-release | $124,906 | +9.8% | 10 | -13 | $12,490 | $265,945 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 8 | - | Dear John | $123,987 | - | 23 | - | $5,390 | $228,230 | 1 | A-Film Distribution | true | false |
| 9 | 4 | 22 Bullets | $112,425 | -5.8% | 15 | - | $7,495 | $261,871 | 2 | Belga Films | false | false |
| 10 | 6 | Avatar | $96,221 | -4.9% | 51 | -6 | $1,886 | $14,878,426 | 16 | 20th Century Fox International | false | false |
| 11 | 7 | The Round Up | $84,325 | -14% | 21 | -2 | $4,015 | $611,736 | 4 | Belga Films | false | false |
| 12 | 8 | Bo | $46,220 | -25.4% | 23 | - | $2,009 | $1,537,201 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 13 | - | The Spy Next Door 2010 Re-release | $45,410 | - | 11 | - | $4,128 | $45,410 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 14 | 10 | All That Glitters | $41,849 | -18% | 12 | - | $3,487 | $105,024 | 2 | Alternative Films | false | false |
| 15 | 11 | The Princess and the Frog | $35,887 | -28.1% | 46 | -17 | $780 | $3,414,259 | 9 | Walt Disney Pictures | false | false |
| 16 | 9 | Case 39 | $35,708 | -39.7% | 19 | -4 | $1,879 | $338,155 | 3 | Universal Pictures International (UPI) | false | false |
| 17 | - | Vicky the Viking | $34,220 | - | 19 | - | $1,801 | $36,568 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 18 | 12 | The Pimp | $24,455 | -33.7% | 11 | -5 | $2,223 | $796,936 | 7 | Belga Films | false | false |
| 19 | 19 | Heartbreaker | $23,398 | +14% | 23 | +2 | $1,017 | $90,591 | 3 | N/A | false | false |
| 20 | 17 | A Single Man | $17,133 | -31.9% | 9 | -2 | $1,903 | $356,531 | 6 | Cinéart | false | false |
| 21 | 15 | Desert Flower 2009 Re-release | $16,645 | -38.3% | 7 | -4 | $2,377 | $173,402 | 3 | Cinéart | false | false |
| 22 | 14 | From Paris with Love | $14,783 | -45.4% | 13 | -8 | $1,137 | $443,332 | 6 | Belga Films | false | false |
| 23 | 13 | Percy Jackson & the Olympians: The Lightning Thief | $14,528 | -48% | 54 | -5 | $269 | $2,068,440 | 8 | 20th Century Fox International | false | false |
| 24 | 18 | Precious | $13,089 | -47.3% | 13 | -1 | $1,006 | $251,204 | 5 | A-Film Distribution | false | false |
| 25 | 16 | Edge of Darkness | $11,110 | -57.6% | 5 | -13 | $2,222 | $699,662 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 26 | 24 | Valentine's Day | $10,862 | +0.2% | 21 | - | $517 | $1,583,624 | 8 | 20th Century Fox International | false | false |
| 27 | 21 | Chloe | $7,963 | -59.7% | 7 | -8 | $1,137 | $211,299 | 4 | Universal Pictures International (UPI) | false | false |
| 28 | 20 | Alvin and the Chipmunks: The Squeakquel | $7,716 | -61.6% | 15 | -16 | $514 | $4,450,183 | 15 | 20th Century Fox International | false | false |
| 29 | 23 | The Hurt Locker | $6,233 | -57.2% | 6 | - | $1,038 | $312,550 | 28 | Belga Films | false | false |
| 30 | 29 | Oceans | $5,441 | -1.9% | 11 | -2 | $494 | $721,871 | 10 | Alternative Films | false | false |
| 31 | 25 | The Wolfman | $5,381 | -32.6% | 2 | -5 | $2,690 | $1,097,189 | 8 | Universal Pictures International (UPI) | false | false |
| 32 | 27 | Dossier K. | $5,205 | -17.6% | 2 | -2 | $2,602 | $3,721,610 | 17 | Kinepolis Film Distribution (KFD) | false | false |
| 33 | 33 | A Serious Man | $4,094 | +1.7% | 7 | -3 | $584 | $488,236 | 11 | Universal Pictures International (UPI) | false | false |
| 34 | 35 | Devil's Kickers | $3,711 | +1% | 3 | - | $1,237 | $18,726 | 4 | Universal Pictures International (UPI) | false | false |
| 35 | 34 | The Book of Eli | $3,506 | -12% | 1 | -1 | $3,506 | $578,891 | 9 | Paradiso Entertainment | false | false |
| 36 | 30 | Crazy Heart | $3,415 | -37.9% | 4 | -1 | $853 | $59,993 | 5 | 20th Century Fox International | false | false |
| 37 | 32 | Dumas | $3,139 | -27.5% | 8 | - | $392 | $33,973 | 3 | Benelux Film Distributors | false | false |
| 38 | 28 | Cloudy with a Chance of Meatballs | $2,999 | -51.1% | 4 | -3 | $749 | $1,095,226 | 12 | Sony Pictures Releasing | false | false |
| 39 | 37 | Mr. Nobody | $2,689 | -1.8% | 9 | +4 | $298 | $835,899 | 12 | Belga Films | false | false |
| 40 | 22 | Planet 51 | $2,543 | -83.5% | 26 | -14 | $97 | $854,796 | 8 | Belga Films | false | false |
| 41 | - | The Wolberg Family | $1,955 | - | 3 | - | $651 | $2,867 | 1 | N/A | true | false |
| 42 | - | Little Girl | $1,616 | - | 2 | - | $808 | $1,709 | 1 | N/A | true | false |
| 43 | 26 | I Love You Phillip Morris | $1,268 | -82.4% | 4 | -8 | $317 | $393,388 | 7 | Belga Films | false | false |
| 44 | 39 | White as Snow | $1,135 | -52.1% | 4 | -2 | $283 | $24,478 | 3 | Benelux Film Distributors | false | false |
| 45 | 45 | Fantastic Mr. Fox | $984 | +19.1% | 6 | -3 | $164 | $76,460 | 7 | 20th Century Fox International | false | false |
| 46 | 40 | Everybody's Fine | $826 | -62.3% | 4 | -1 | $206 | $14,067 | 3 | Walt Disney Pictures | false | false |
| 47 | 42 | Coursier | $804 | -62.7% | 2 | -4 | $402 | $115,203 | 5 | Belga Films | false | false |
| 48 | 49 | The Girl Who Played with Fire | $398 | +337.4% | 1 | - | $398 | $195,327 | 12 | Benelux Film Distributors | false | false |
| 49 | - | Sunshine Barry and the Disco Worms | $380 | - | 13 | - | $29 | $380 | 1 | N/A | true | false |
