| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | How to Train Your Dragon | $2,434,141 | - | 384 | - | $6,338 | $2,434,141 | 1 | Paramount Pictures International | true | false |
| 2 | 1 | The Book of Eli | $745,892 | -31% | 185 | -10 | $4,031 | $2,219,856 | 2 | Sony Pictures Releasing | false | false |
| 3 | 2 | Shutter Island | $563,913 | -29.1% | 184 | -2 | $3,064 | $3,120,328 | 3 | Paramount Pictures International | false | false |
| 4 | 3 | The Blind Side | $541,081 | -26.5% | 106 | -9 | $5,104 | $1,509,741 | 2 | Warner Bros. | false | false |
| 5 | 5 | It's Complicated | $262,632 | -36.2% | 148 | -18 | $1,774 | $4,107,798 | 5 | Universal Pictures International (UPI) | false | false |
| 6 | 7 | Remember Me | $213,721 | -44% | 149 | -4 | $1,434 | $1,476,454 | 3 | Paris Filmes | false | false |
| 7 | 6 | Percy Jackson & the Olympians: The Lightning Thief | $206,081 | -47.5% | 262 | -14 | $786 | $8,493,514 | 7 | 20th Century Fox International | false | false |
| 8 | - | Did You Hear About the Morgans? | $205,925 | - | 61 | - | $3,375 | $205,925 | 1 | Sony Pictures Releasing | true | false |
| 9 | - | The Box | $158,732 | - | 50 | - | $3,174 | $158,732 | 1 | N/A | true | false |
| 10 | 8 | Valentine's Day | $132,078 | -47.4% | 136 | -19 | $971 | $4,018,220 | 6 | Warner Bros. | false | false |
| 11 | 4 | Avatar | $85,038 | -87.1% | 57 | -119 | $1,491 | $56,328,195 | 15 | 20th Century Fox International | false | false |
| 12 | - | Halloween II | $52,109 | - | 52 | - | $1,002 | $52,109 | 1 | PlayArte Pictures | true | false |
| 13 | - | The Men Who Stare at Goats | $42,523 | - | 10 | - | $4,252 | $42,975 | 1 | Sony Pictures Releasing | true | false |
| 14 | 13 | The Hurt Locker | $41,932 | -45.2% | 29 | -24 | $1,445 | $700,097 | 8 | N/A | false | false |
| 15 | 14 | Tooth Fairy | $32,996 | -55.4% | 102 | -32 | $323 | $5,044,762 | 10 | 20th Century Fox International | false | false |
| 16 | 16 | Carriers | $30,401 | -30.3% | 45 | -12 | $675 | $352,399 | 4 | PlayArte Pictures | false | false |
| 17 | 11 | Alvin and the Chipmunks: The Squeakquel | $29,906 | -68.2% | 12 | -160 | $2,492 | $21,512,276 | 12 | 20th Century Fox International | false | false |
| 18 | 10 | Love Happens | $28,616 | -74.6% | 46 | -69 | $622 | $1,086,795 | 4 | PlayArte Pictures | false | false |
| 19 | 12 | The Wolfman | $28,272 | -67.4% | 70 | -67 | $403 | $4,152,604 | 7 | Universal Pictures International (UPI) | false | false |
| 20 | - | Amelia | $20,358 | - | 10 | - | $2,035 | $20,617 | 1 | 20th Century Fox International | true | false |
| 21 | 27 | Xuxa and the Mystery of the Little Ugly Princess | $18,264 | -6.4% | 87 | +18 | $209 | $4,608,589 | 14 | PlayArte Pictures | false | false |
| 22 | 18 | Precious | $13,606 | -55.2% | 28 | -23 | $485 | $876,942 | 7 | PlayArte Pictures | false | false |
| 23 | 26 | An Education | $12,920 | -36.2% | 11 | -1 | $1,174 | $297,946 | 6 | Sony Pictures Releasing | false | false |
| 24 | 23 | High School Musical: O Desafio | $12,894 | -42.1% | 59 | -5 | $218 | $1,054,464 | 8 | Walt Disney Pictures | false | false |
| 25 | 15 | The Final Destination | $11,938 | -83.2% | 45 | -69 | $265 | $4,547,387 | 8 | PlayArte Pictures | false | false |
| 26 | 17 | Invictus | $11,017 | -65.3% | 30 | -16 | $367 | $1,923,500 | 9 | Warner Bros. | false | false |
| 27 | 9 | Toy Story 2 2009 Re-release | $9,185 | -95.8% | 3 | -94 | $3,061 | $1,223,991 | 4 | Walt Disney Pictures | false | false |
| 28 | 33 | Zombieland | $4,714 | -9.7% | 21 | -1 | $224 | $400,424 | 9 | Sony Pictures Releasing | false | false |
| 29 | 24 | The Lovely Bones | $4,540 | -79.1% | 29 | -39 | $156 | $1,612,729 | 6 | Paramount Pictures International | false | false |
| 30 | 39 | Easy Virtue | $3,095 | +412.4% | 6 | - | $515 | $187,079 | 23 | Sony Pictures Releasing | false | false |
| 31 | 37 | Nine | $1,683 | +20.4% | 7 | +3 | $240 | $496,543 | 9 | Sony Pictures Releasing | false | false |
| 32 | 36 | Julie & Julia | $729 | -62.5% | 4 | -4 | $182 | $1,259,396 | 18 | Sony Pictures Releasing | false | false |
| 33 | 38 | The Princess and the Frog | $454 | -52.4% | 4 | -4 | $113 | $3,909,989 | 16 | Walt Disney Pictures | false | false |
| 34 | 40 | A Christmas Carol | $165 | -30.7% | 1 | - | $165 | $3,007,754 | 21 | Walt Disney Pictures | false | false |
