| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Alice in Wonderland | $748,242 | -27.1% | 80 | - | $9,353 | $2,160,835 | 2 | Walt Disney Pictures | false | false |
| 2 | - | Green Zone | $191,022 | - | 53 | - | $3,604 | $195,771 | 1 | United International Pictures | true | false |
| 3 | 2 | Shutter Island | $139,459 | -34.9% | 35 | -19 | $3,984 | $1,823,546 | 4 | United International Pictures | false | false |
| 4 | 3 | The Princess and the Frog | $120,465 | -14.7% | 70 | -4 | $1,720 | $1,389,562 | 4 | Walt Disney Pictures | false | false |
| 5 | - | The Blind Side | $97,206 | - | 25 | - | $3,888 | $99,653 | 1 | Sandrew Metronome Distribution Sverige AB | true | false |
| 6 | 4 | East End Angels | $77,941 | -13.8% | 42 | -6 | $1,855 | $362,952 | 3 | Nordisk Film | false | false |
| 7 | 5 | Avatar | $72,584 | -18.1% | 17 | -7 | $4,269 | $13,704,447 | 13 | 20th Century Fox International | false | false |
| 8 | 6 | The Junior Olsen Gang and the Master Thief | $44,461 | -38.6% | 47 | -8 | $945 | $1,982,587 | 7 | Nordisk Film | false | false |
| 9 | 7 | The Lovely Bones | $33,899 | -52.2% | 34 | -11 | $997 | $140,431 | 2 | United International Pictures | false | false |
| 10 | 10 | Crazy Heart | $30,608 | -12.5% | 18 | -8 | $1,700 | $217,062 | 3 | 20th Century Fox International | false | false |
| 11 | 8 | Edge of Darkness | $30,461 | -54.4% | 18 | -8 | $1,692 | $125,038 | 2 | Nordisk Film | false | false |
| 12 | 14 | Alvin and the Chipmunks: The Squeakquel | $27,094 | -2.6% | 13 | -1 | $2,084 | $3,309,733 | 12 | 20th Century Fox International | false | false |
| 13 | 11 | Percy Jackson & the Olympians: The Lightning Thief | $21,017 | -39.1% | 30 | -6 | $700 | $688,402 | 5 | 20th Century Fox International | false | false |
| 14 | 13 | The Wolfman | $20,697 | -26.7% | 31 | +4 | $667 | $749,254 | 5 | United International Pictures | false | false |
| 15 | 9 | Valentine's Day | $19,402 | -53.8% | 12 | -9 | $1,616 | $870,693 | 5 | Sandrew Metronome Distribution Sverige AB | false | false |
| 16 | 16 | Cloudy with a Chance of Meatballs | $19,121 | -4.2% | 26 | -7 | $735 | $1,290,917 | 9 | Sony Pictures Releasing | false | false |
| 17 | 17 | Fantastic Mr. Fox | $17,454 | -4.6% | 27 | -2 | $646 | $440,073 | 6 | 20th Century Fox International | false | false |
| 18 | 15 | Ploddy the Police Car Makes a Splash | $16,820 | -24.6% | 17 | -10 | $989 | $1,406,554 | 10 | Nordisk Film | false | false |
| 19 | 12 | The Road | $15,167 | -52.8% | 9 | -1 | $1,685 | $311,700 | 4 | Scanbox Entertainment | false | false |
| 20 | 19 | Precious | $12,015 | -26.3% | 7 | -1 | $1,716 | $394,361 | 7 | N/A | false | false |
| 21 | 18 | A Single Man | $11,036 | -32.7% | 5 | - | $2,207 | $208,043 | 5 | Svensk Filmindustri (SF) | false | false |
| 22 | 23 | Did You Hear About the Morgans? | $3,069 | -48.8% | 16 | -9 | $191 | $440,966 | 7 | Sony Pictures Releasing | false | false |
| 23 | 25 | The Imaginarium of Doctor Parnassus | $311 | -53.9% | 4 | -2 | $77 | $372,334 | 12 | Sony Pictures Releasing | false | false |
