| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Alice in Wonderland | $560,869 | -33.5% | 116 | -1 | $4,835 | $3,238,155 | 3 | Walt Disney Pictures | false | false |
| 2 | 2 | Avatar | $162,367 | -35.4% | 26 | -2 | $6,244 | $22,252,998 | 14 | 20th Century Fox International | false | false |
| 3 | 4 | The Lovely Bones | $162,084 | -5.1% | 54 | - | $3,001 | $474,753 | 2 | United International Pictures | false | false |
| 4 | 3 | Couples Therapy | $134,171 | -25.4% | 70 | -8 | $1,916 | $1,532,631 | 4 | Nordisk Film | false | false |
| 5 | 5 | Shutter Island | $111,572 | -16.8% | 33 | -2 | $3,380 | $1,455,172 | 5 | United International Pictures | false | false |
| 6 | 6 | Father of Four | $85,088 | -25.9% | 67 | - | $1,269 | $4,701,341 | 7 | Scanbox Entertainment | false | false |
| 7 | 7 | The Princess and the Frog | $66,895 | -28.2% | 73 | +4 | $916 | $2,134,759 | 6 | Walt Disney Pictures | false | false |
| 8 | 8 | A Single Man | $64,424 | -4.9% | 9 | -1 | $7,158 | $299,830 | 3 | Filmcompagniet | false | false |
| 9 | 9 | From Paris with Love | $36,584 | -28.5% | 13 | - | $2,814 | $133,429 | 2 | Nordisk Film | false | false |
| 10 | 10 | Precious | $33,109 | -24% | 14 | - | $2,364 | $792,641 | 7 | Miracle Films | false | false |
| 11 | 11 | Invictus | $26,906 | -29.4% | 19 | - | $1,416 | $325,609 | 4 | Sandrew Metronome Distribution Sverige AB | false | false |
| 12 | 13 | Cloudy with a Chance of Meatballs | $26,088 | -14.9% | 45 | -5 | $579 | $1,781,282 | 9 | Sony Pictures Releasing | false | false |
| 13 | 12 | Percy Jackson & the Olympians: The Lightning Thief | $25,741 | -29.8% | 37 | -12 | $695 | $1,127,223 | 6 | 20th Century Fox International | false | false |
| 14 | 14 | Alvin and the Chipmunks: The Squeakquel | $20,840 | -11.4% | 23 | -2 | $906 | $3,789,513 | 13 | 20th Century Fox International | false | false |
| 15 | 16 | It's Complicated | $16,707 | -8.7% | 29 | +8 | $576 | $1,139,161 | 9 | United International Pictures | false | false |
| 16 | - | Welcome | $14,726 | - | 4 | - | $3,681 | $14,726 | 1 | Camera Film | true | false |
| 17 | 17 | Up in the Air | $13,852 | -15% | 12 | +1 | $1,154 | $696,273 | 8 | United International Pictures | false | false |
| 18 | - | Brothers | $12,614 | - | 9 | - | $1,401 | $12,614 | 1 | United International Pictures | true | false |
| 19 | - | The Road | $12,357 | - | 15 | - | $823 | $605,425 | 8 | Scanbox Entertainment | false | false |
| 20 | 15 | Valentine's Day | $11,490 | -44.3% | 20 | -8 | $574 | $1,062,220 | 6 | Sandrew Metronome Distribution Sverige AB | false | false |
| 21 | 19 | A Prophet | $9,737 | -25% | 2 | -1 | $4,868 | $89,692 | 4 | Sony Pictures Releasing | false | false |
| 22 | - | Legion | $5,396 | - | 1 | - | $5,396 | $5,396 | 1 | Sony Pictures Releasing | true | false |
| 23 | 21 | The Imaginarium of Doctor Parnassus | $5,048 | -12.3% | 7 | -3 | $721 | $738,428 | 13 | Sony Pictures Releasing | false | false |
