| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Alice in Wonderland | $672,714 | -39.9% | 96 | +3 | $7,007 | $2,067,347 | 2 | Walt Disney Pictures | false | false |
| 2 | 2 | It's Complicated | $244,098 | -40.7% | 69 | -1 | $3,537 | $772,298 | 2 | United International Pictures | false | false |
| 3 | - | The Book of Eli | $164,335 | - | 33 | - | $4,979 | $164,335 | 1 | Sony Pictures Releasing | true | false |
| 4 | 3 | Shutter Island | $133,341 | -47% | 61 | -1 | $2,185 | $907,719 | 3 | Zon Lusomundo Audiovisuais | false | false |
| 5 | - | The Lovely Bones | $66,664 | - | 24 | - | $2,777 | $66,664 | 1 | Zon Lusomundo Audiovisuais | true | false |
| 6 | 4 | The Wolfman | $59,663 | -53.1% | 51 | -12 | $1,169 | $899,104 | 4 | Zon Lusomundo Audiovisuais | false | false |
| 7 | 5 | Avatar | $58,701 | -43% | 32 | -12 | $1,834 | $9,482,726 | 13 | 20th Century Fox International | false | false |
| 8 | 6 | The Princess and the Frog | $51,617 | -49.8% | 43 | -8 | $1,200 | $1,519,969 | 6 | Walt Disney Pictures | false | false |
| 9 | - | The Hurt Locker | $44,357 | - | 7 | - | $6,336 | $149,876 | 26 | Zon Lusomundo Audiovisuais | false | false |
| 10 | 7 | The Spy Next Door 2010 Re-release | $33,240 | -50.1% | 22 | +2 | $1,510 | $205,274 | 3 | Prisvídeo | false | false |
| 11 | 9 | Invictus | $28,959 | -36.9% | 24 | -3 | $1,206 | $1,191,226 | 7 | Warner Bros. | false | false |
| 12 | 8 | Cloudy with a Chance of Meatballs | $27,966 | -45% | 24 | -1 | $1,165 | $851,085 | 5 | Sony Pictures Releasing | false | false |
| 13 | 14 | Precious | $19,751 | -10.1% | 13 | - | $1,519 | $237,545 | 5 | N/A | false | false |
| 14 | 11 | A Single Man | $15,709 | -38.2% | 7 | - | $2,244 | $158,226 | 4 | Prisvídeo | false | false |
| 15 | 12 | Up in the Air | $14,368 | -42.4% | 18 | -3 | $798 | $1,344,436 | 8 | Zon Lusomundo Audiovisuais | false | false |
| 16 | 15 | Valentine's Day | $8,433 | -53.6% | 17 | -10 | $496 | $670,782 | 5 | Warner Bros. | false | false |
| 17 | 21 | Nine | $6,392 | +92.6% | 15 | +3 | $426 | $551,727 | 9 | Castello Lopes Multimédia | false | false |
| 18 | 13 | Percy Jackson & the Olympians: The Lightning Thief | $6,229 | -74.5% | 15 | -4 | $415 | $390,114 | 5 | Castello Lopes Multimédia | false | false |
| 19 | 19 | A Serious Man | $4,526 | -40.1% | 2 | -2 | $2,263 | $60,937 | 4 | Castello Lopes Multimédia | false | false |
| 20 | 16 | The Men Who Stare at Goats | $4,365 | -69.4% | 12 | -3 | $363 | $515,730 | 6 | Prisvídeo | false | false |
| 21 | 20 | Agora | $2,696 | -45.4% | 6 | -1 | $449 | $569,083 | 14 | Castello Lopes Multimédia | false | false |
| 22 | 23 | The Messenger | $1,399 | -5.3% | 3 | -3 | $466 | $17,830 | 3 | Zon Lusomundo Audiovisuais | false | false |
| 23 | 24 | Antichrist | $725 | -33.5% | 2 | - | $362 | $72,842 | 7 | Prisvídeo | false | false |
| 24 | 27 | My One and Only | $716 | -21.4% | 2 | -3 | $358 | $28,258 | 5 | Zon Lusomundo Audiovisuais | false | false |
| 25 | 25 | Couples Retreat | $694 | -34.5% | 1 | - | $694 | $1,287,880 | 15 | Zon Lusomundo Audiovisuais | false | false |
| 26 | 26 | The Cove | $656 | -30.4% | 4 | - | $164 | $5,835 | 3 | Prisvídeo | false | false |
| 27 | 28 | Did You Hear About the Morgans? | $50 | -84.6% | 2 | - | $25 | $711,370 | 10 | Sony Pictures Releasing | false | false |
