| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Alice in Wonderland | $804,405 | - | 84 | - | $9,576 | $804,405 | 1 | Walt Disney Pictures | true | false |
| 2 | - | Mao's Last Dancer | $206,488 | - | 61 | - | $3,385 | $217,725 | 1 | Hopscotch Films | true | false |
| 3 | 1 | Avatar | $109,864 | -42.1% | 49 | -8 | $2,242 | $11,286,530 | 12 | 20th Century Fox International | false | false |
| 4 | 2 | Shutter Island | $104,075 | -29.1% | 43 | - | $2,420 | $592,340 | 3 | Paramount Pictures International | false | false |
| 5 | 3 | Valentine's Day | $75,010 | -46.4% | 48 | - | $1,562 | $1,319,379 | 4 | Warner Bros. | false | false |
| 6 | 4 | From Paris with Love | $56,874 | -33.6% | 40 | - | $1,421 | $180,301 | 2 | Hoyts Distribution | false | false |
| 7 | 5 | Percy Jackson & the Olympians: The Lightning Thief | $48,443 | -41.2% | 57 | -3 | $849 | $584,814 | 4 | 20th Century Fox International | false | false |
| 8 | 8 | Crazy Heart | $37,938 | -22.5% | 22 | - | $1,724 | $109,256 | 2 | 20th Century Fox International | false | false |
| 9 | - | Carmen | $37,721 | - | 15 | - | $2,514 | $37,721 | 1 | Rialto Distribution | true | false |
| 10 | 6 | Bright Star | $33,112 | -39.6% | 27 | -1 | $1,226 | $230,053 | 3 | Hopscotch Films | false | false |
| 11 | 7 | It's Complicated | $30,231 | -39.9% | 49 | -7 | $616 | $1,451,008 | 7 | United International Pictures | false | false |
| 12 | 9 | Precious | $23,360 | -34.9% | 36 | -2 | $648 | $389,329 | 5 | Icon Film Distribution | false | false |
| 13 | 11 | The Girl with the Dragon Tattoo | $19,006 | -17.4% | 38 | +3 | $500 | $686,754 | 12 | Rialto Distribution | false | false |
| 14 | 10 | The Wolfman | $17,381 | -50.5% | 26 | -16 | $668 | $354,474 | 4 | United International Pictures | false | false |
| 15 | 15 | Up in the Air | $8,857 | -30.8% | 23 | -2 | $385 | $588,353 | 8 | Paramount Pictures International | false | false |
| 16 | 13 | 9 | $8,324 | -52.6% | 14 | - | $594 | $32,182 | 2 | Madman Entertainment | false | false |
| 17 | - | Atithi Tum Kab Jaoge? | $5,688 | - | 2 | - | $2,844 | $5,688 | 1 | Forum Hungary | true | false |
| 18 | 14 | My Name Is Khan | $5,560 | -67.8% | 10 | -1 | $556 | $225,358 | 4 | 20th Century Fox International | false | false |
| 19 | 20 | Alvin and the Chipmunks: The Squeakquel | $5,359 | -31.5% | 29 | -9 | $184 | $2,708,665 | 11 | 20th Century Fox International | false | false |
| 20 | 18 | The Lovely Bones | $4,701 | -45.7% | 20 | -19 | $235 | $2,388,913 | 11 | Paramount Pictures International | false | false |
| 21 | 21 | Tooth Fairy | $4,582 | -34.1% | 22 | -6 | $208 | $824,100 | 8 | 20th Century Fox International | false | false |
| 22 | 17 | Sherlock Holmes | $4,292 | -52.5% | 22 | -14 | $195 | $2,690,356 | 11 | Roadshow Films | false | false |
| 23 | 16 | Nine | $4,273 | -57.2% | 19 | -5 | $224 | $420,125 | 58 | Sony Pictures Releasing | false | false |
| 24 | 25 | Fantastic Mr. Fox | $3,977 | -12.7% | 19 | -2 | $209 | $555,741 | 9 | 20th Century Fox International | false | false |
| 25 | 19 | Invictus | $3,951 | -52% | 28 | -17 | $141 | $331,707 | 6 | Warner Bros. | false | false |
| 26 | 22 | Edge of Darkness | $3,437 | -47.8% | 14 | -5 | $245 | $227,743 | 5 | Icon Film Distribution | false | false |
| 27 | 23 | Did You Hear About the Morgans? | $2,633 | -59.8% | 9 | -14 | $292 | $259,171 | 5 | Sony Pictures Releasing | false | false |
| 28 | 24 | Max Manus: Man of War | $2,204 | -56.8% | 14 | +2 | $157 | $20,998 | 3 | Rialto Distribution | false | false |
| 29 | 26 | Karthik Calling Karthik | $1,467 | -50.7% | 2 | -1 | $733 | $6,022 | 2 | - | false | false |
| 30 | 28 | Little Big Soldier | $913 | -51.2% | 2 | -1 | $456 | $15,137 | 4 | Vendetta Films | false | false |
| 31 | 30 | Silent Wedding | $894 | -45.4% | 4 | -1 | $223 | $10,951 | 4 | Vendetta Films | false | false |
| 32 | - | Creation | $812 | - | 4 | - | $203 | $117,789 | 11 | Icon Film Distribution | false | false |
| 33 | 38 | The Twilight Saga: New Moon | $753 | +3.3% | 2 | - | $376 | $4,280,053 | 16 | Hoyts Distribution | false | false |
| 34 | 32 | Paranormal Activity | $504 | -67.5% | 2 | -5 | $252 | $908,785 | 10 | Icon Film Distribution | false | false |
| 35 | 35 | Astro Boy | $405 | -56% | 6 | -2 | $67 | $172,936 | 7 | Hoyts Distribution | false | false |
| 36 | 29 | Teen Patti | $393 | -77.2% | 2 | - | $196 | $2,854 | 2 | Mind Blowing Films | false | false |
| 37 | 33 | Balibo | $390 | -65% | 2 | -3 | $195 | $7,175 | 3 | Paramount Pictures International | false | false |
| 38 | 37 | The Imaginarium of Doctor Parnassus | $347 | -55.2% | 1 | - | $347 | $252,153 | 18 | Hoyts Distribution | false | false |
| 39 | 39 | The Time Traveler's Wife | $310 | -53% | 1 | -9 | $310 | $618,569 | 14 | Roadshow Films | false | false |
| 40 | - | Looking for Eric | $162 | - | 2 | - | $81 | $116,836 | 15 | Icon Film Distribution | false | false |
| 41 | - | Mary and Max | $138 | - | 1 | - | $138 | $54,197 | 15 | Icon Film Distribution | false | false |
| 42 | 36 | An Education | $92 | -88.1% | 4 | - | $23 | $601,527 | 22 | Paramount Pictures International | false | false |
| 43 | - | Noodle | $73 | - | 2 | - | $36 | $21,337 | 7 | - | false | false |
| 44 | - | Where the Wild Things Are | $52 | - | 3 | - | $17 | $892,855 | 14 | Roadshow Films | false | false |
| 45 | - | Planet 51 | $52 | - | 1 | - | $52 | $285,431 | 13 | Hoyts Distribution | false | false |
