| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Alice in Wonderland | $586,160 | - | 70 | - | $8,373 | $649,718 | 1 | Walt Disney Pictures | true | false |
| 2 | - | Shutter Island | $201,340 | - | 34 | - | $5,921 | $282,440 | 1 | United International Pictures | true | false |
| 3 | 2 | The Wolfman | $57,812 | -70.3% | 29 | -24 | $1,993 | $883,933 | 3 | United International Pictures | false | false |
| 4 | 1 | Percy Jackson & the Olympians: The Lightning Thief | $52,434 | -73.8% | 20 | -23 | $2,621 | $1,343,752 | 4 | 20th Century Fox International | false | false |
| 5 | 3 | Up in the Air | $27,007 | -53.9% | 11 | -2 | $2,455 | $124,757 | 2 | United International Pictures | false | false |
| 6 | 5 | Avatar | $10,613 | +27% | 4 | - | $2,653 | $5,895,469 | 12 | 20th Century Fox International | false | false |
| 7 | 7 | Legion | $10,474 | +83.9% | 8 | +1 | $1,309 | $657,159 | 6 | Sony Pictures Releasing | false | false |
| 8 | 6 | Sherlock Holmes | $9,698 | +55.2% | 3 | -1 | $3,232 | $2,143,214 | 10 | Warner Bros. | false | false |
| 9 | 4 | Valentine's Day | $4,611 | -73.4% | 6 | -2 | $768 | $426,317 | 4 | Warner Bros. | false | false |
| 10 | 9 | Case 39 | $3,536 | +38% | 2 | - | $1,768 | $95,247 | 6 | United International Pictures | false | false |
| 11 | 10 | Ninja Assassin | $687 | +252.3% | 1 | - | $687 | $1,838,711 | 15 | Warner Bros. | false | false |
