| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Alice in Wonderland | $1,182,994 | - | 172 | - | $6,877 | $1,182,994 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Avatar | $98,611 | -62.9% | 23 | -41 | $4,287 | $13,311,118 | 12 | 20th Century Fox International | false | false |
| 3 | 3 | The Wolfman | $88,450 | -42.5% | 85 | -5 | $1,040 | $943,825 | 4 | United International Pictures | false | false |
| 4 | 4 | Percy Jackson & the Olympians: The Lightning Thief | $73,407 | -43% | 67 | -15 | $1,095 | $739,902 | 4 | 20th Century Fox International | false | false |
| 5 | - | [Rec]² | $69,926 | - | 32 | - | $2,185 | $69,926 | 1 | Cine Colombia | true | false |
| 6 | 5 | Law Abiding Citizen | $54,440 | -41.1% | 51 | -3 | $1,067 | $192,224 | 2 | Cineplex | false | false |
| 7 | 6 | Tooth Fairy | $48,620 | -34.2% | 46 | -6 | $1,056 | $1,054,472 | 7 | 20th Century Fox International | false | false |
| 8 | 8 | Precious | $41,812 | -24.6% | 19 | - | $2,200 | $209,233 | 3 | Cine Colombia | false | false |
| 9 | 7 | Couples Retreat | $34,107 | -39.5% | 27 | +1 | $1,263 | $115,465 | 2 | United International Pictures | false | false |
| 10 | 9 | Valentine's Day | $32,488 | -39.7% | 28 | -4 | $1,160 | $360,814 | 4 | Warner Bros. | false | false |
| 11 | - | The Imaginarium of Doctor Parnassus | $24,304 | - | 9 | - | $2,700 | $24,304 | 1 | Sony Pictures Releasing | true | false |
| 12 | 11 | Invictus | $22,990 | -22.7% | 26 | - | $884 | $337,972 | 5 | Warner Bros. | false | false |
| 13 | 10 | Old Dogs | $15,690 | -52.2% | 25 | -20 | $627 | $1,146,620 | 9 | Walt Disney Pictures | false | false |
| 14 | 14 | The Hurt Locker | $14,780 | +8.4% | 10 | -1 | $1,478 | $107,622 | 4 | Cineplex | false | false |
| 15 | 13 | The Lovely Bones | $12,534 | -38.9% | 25 | - | $501 | $94,654 | 3 | United International Pictures | false | false |
| 16 | 12 | Cirque du Freak: The Vampire's Assistant | $11,871 | -55.3% | 23 | -12 | $516 | $110,784 | 3 | United International Pictures | false | false |
| 17 | 15 | An Education | $8,840 | -4.4% | 6 | - | $1,473 | $42,295 | 3 | Sony Pictures Releasing | false | false |
| 18 | - | The White Ribbon | $7,580 | - | 6 | - | $1,263 | $7,580 | 1 | Babilla Ciné | true | false |
| 19 | 21 | The Soloist | $3,574 | -11.9% | 5 | - | $714 | $64,684 | 8 | United International Pictures | false | false |
| 20 | 18 | Broken Embraces | $3,538 | -46.1% | 7 | -4 | $505 | $99,441 | 5 | United International Pictures | false | false |
| 21 | 26 | Ninja Assassin | $2,913 | +35.8% | 4 | -1 | $728 | $139,229 | 6 | Warner Bros. | false | false |
| 22 | 19 | Up in the Air | $2,605 | -60.1% | 6 | -6 | $434 | $249,162 | 7 | United International Pictures | false | false |
| 23 | 17 | Alvin and the Chipmunks: The Squeakquel | $2,545 | -67% | 10 | -21 | $254 | $1,398,431 | 10 | 20th Century Fox International | false | false |
| 24 | 20 | Nine | $2,024 | -50.5% | 4 | -2 | $506 | $124,753 | 6 | Sony Pictures Releasing | false | false |
| 25 | - | Taking Woodstock | $1,903 | - | 3 | - | $634 | $1,903 | 1 | United International Pictures | true | false |
| 26 | 25 | Departures | $1,878 | -29.4% | 5 | +1 | $375 | $112,220 | 8 | Cine Colombia | false | false |
| 27 | 28 | Zombieland | $1,586 | -1.8% | 2 | +1 | $793 | $165,261 | 8 | Sony Pictures Releasing | false | false |
| 28 | 16 | Fame | $1,340 | -84.3% | 7 | -8 | $191 | $13,218 | 2 | Cine Colombia | false | false |
| 29 | 22 | The Princess and the Frog | $938 | -76.5% | 6 | -13 | $156 | $18,722,327 | 11 | Walt Disney Pictures | false | false |
| 30 | 2 | Toy Story 2 2009 Re-release | $701 | -99.6% | 2 | -34 | $350 | $219,268 | 2 | Walt Disney Pictures | false | false |
| 31 | 29 | The Stepfather | $653 | -50.3% | 1 | -1 | $653 | $97,801 | 13 | Sony Pictures Releasing | false | false |
| 32 | 23 | Astro Boy | $625 | -79.7% | 3 | -4 | $208 | $77,549 | 8 | Cine Colombia | false | false |
