| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Shutter Island | $8,199,990 | - | 500 | - | $16,399 | $8,199,990 | 1 | Paramount Pictures International | true | false |
| 2 | 3 | Avatar | $3,153,365 | -31.4% | 449 | -80 | $7,023 | $157,070,899 | 11 | 20th Century Fox International | false | false |
| 3 | 1 | The Princess and the Frog | $3,093,845 | -37.1% | 689 | -11 | $4,490 | $29,713,316 | 5 | Walt Disney Pictures | false | false |
| 4 | 4 | The Pimp | $2,991,939 | -32.8% | 470 | +5 | $6,365 | $8,430,888 | 2 | N/A | false | false |
| 5 | 2 | Valentine's Day | $2,264,321 | -52.7% | 418 | +10 | $5,417 | $8,016,859 | 2 | Warner Bros. | false | false |
| 6 | 6 | Oceans | $1,877,992 | -27.5% | 588 | +7 | $3,193 | $21,799,884 | 5 | N/A | false | false |
| 7 | 5 | Sherlock Holmes | $1,875,692 | -33.3% | 616 | -51 | $3,044 | $17,320,210 | 4 | Warner Bros. | false | false |
| 8 | 7 | Percy Jackson & the Olympians: The Lightning Thief | $1,611,970 | -36.9% | 547 | -8 | $2,946 | $9,186,060 | 3 | 20th Century Fox International | false | false |
| 9 | 8 | Planet 51 | $1,276,577 | -20.6% | 495 | +36 | $2,578 | $7,445,507 | 4 | N/A | false | false |
| 10 | - | Coursier | $1,139,092 | - | 241 | - | $4,726 | $1,139,092 | 1 | Europa Filmes | true | false |
| 11 | 12 | Invictus | $924,802 | -29.9% | 434 | -6 | $2,130 | $26,032,144 | 7 | Warner Bros. | false | false |
| 12 | 11 | Together Is Too Much | $707,461 | -46.8% | 280 | +9 | $2,526 | $2,377,203 | 2 | StudioCanal | false | false |
| 13 | 10 | From Paris with Love | $698,378 | -52.8% | 437 | - | $1,598 | $2,572,269 | 2 | Europa Filmes | false | false |
| 14 | 9 | Edge of Darkness | $680,956 | -56.6% | 351 | -6 | $1,940 | $2,578,164 | 2 | Metropolitan Filmexport | false | false |
| 15 | 13 | Fantastic Mr. Fox | $660,781 | -23.5% | 153 | +6 | $4,318 | $1,821,353 | 2 | 20th Century Fox International | false | false |
| 16 | - | Couples Retreat | $616,700 | - | 130 | - | $4,743 | $616,700 | 1 | Universal Pictures International (UPI) | true | false |
| 17 | - | Freedom | $601,252 | - | 95 | - | $6,328 | $601,252 | 1 | UGC Distribution | true | false |
| 18 | - | A Single Man | $588,829 | - | 65 | - | $9,058 | $588,829 | 1 | N/A | true | false |
| 19 | - | An Education | $422,061 | - | 70 | - | $6,029 | $422,061 | 1 | Metropolitan Filmexport | true | false |
| 20 | 14 | I Love You Phillip Morris | $363,156 | -52.4% | 163 | -35 | $2,227 | $2,952,631 | 3 | Europa Filmes | false | false |
| 21 | 15 | The Wolfman | $160,946 | -76.3% | 156 | -203 | $1,031 | $2,947,731 | 3 | Universal Pictures International (UPI) | false | false |
| 22 | 20 | Brothers | $124,444 | -59.5% | 83 | -38 | $1,499 | $2,751,651 | 4 | Wild Bunch Distribution | false | false |
| 23 | - | A Happy Man | $79,921 | - | 55 | - | $1,453 | $79,921 | 1 | N/A | true | false |
