| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Avatar | $618,684 | -29% | 32 | -7 | $19,333 | $21,810,095 | 11 | 20th Century Fox International | false | false |
| 2 | 1 | Father of Four | $533,068 | -48.2% | 92 | -5 | $5,794 | $4,306,905 | 4 | Scanbox Entertainment | false | false |
| 3 | - | Couples Therapy | $486,533 | - | 78 | - | $6,237 | $577,705 | 1 | Nordisk Film | true | false |
| 4 | 3 | The Princess and the Frog | $316,991 | -42.6% | 76 | - | $4,170 | $1,838,883 | 3 | Walt Disney Pictures | false | false |
| 5 | 4 | Shutter Island | $276,380 | -28.9% | 35 | - | $7,896 | $826,163 | 2 | United International Pictures | false | false |
| 6 | 5 | Percy Jackson & the Olympians: The Lightning Thief | $150,929 | -37.4% | 62 | -10 | $2,434 | $979,101 | 3 | 20th Century Fox International | false | false |
| 7 | 6 | Cloudy with a Chance of Meatballs | $126,176 | -35.6% | 59 | -8 | $2,138 | $1,651,729 | 6 | Sony Pictures Releasing | false | false |
| 8 | - | Invictus | $97,637 | - | 20 | - | $4,881 | $135,104 | 1 | Sandrew Metronome Distribution Sverige AB | true | false |
| 9 | 7 | Valentine's Day | $89,561 | -47.8% | 40 | - | $2,239 | $960,118 | 3 | Sandrew Metronome Distribution Sverige AB | false | false |
| 10 | 10 | Precious | $66,537 | -28.1% | 13 | +3 | $5,118 | $602,458 | 4 | Miracle Films | false | false |
| 11 | 8 | Alvin and the Chipmunks: The Squeakquel | $66,200 | -39.6% | 35 | -10 | $1,891 | $3,809,436 | 10 | 20th Century Fox International | false | false |
| 12 | 9 | The Wolfman | $62,462 | -35.5% | 41 | -4 | $1,523 | $520,083 | 3 | United International Pictures | false | false |
| 13 | 11 | It's Complicated | $44,213 | -32.1% | 26 | -5 | $1,700 | $1,043,523 | 6 | United International Pictures | false | false |
| 14 | 12 | Up in the Air | $38,787 | -39.6% | 12 | -1 | $3,232 | $630,805 | 5 | United International Pictures | false | false |
| 15 | 13 | Edge of Darkness | $36,953 | -34.9% | 21 | -7 | $1,759 | $511,592 | 4 | Nordisk Film | false | false |
| 16 | 14 | The Girl Who Kicked the Hornet's Nest | $31,367 | -32.8% | 15 | -4 | $2,091 | $9,224,253 | 14 | Nordisk Film | false | false |
| 17 | 15 | The Road | $30,914 | -18.2% | 14 | -1 | $2,208 | $561,532 | 5 | Scanbox Entertainment | false | false |
| 18 | - | A Prophet | $21,125 | - | 3 | - | $7,041 | $21,125 | 1 | Sony Pictures Releasing | true | false |
| 19 | 16 | Coco Chanel & Igor Stravinsky | $20,089 | -25.9% | 8 | +1 | $2,511 | $137,140 | 3 | Camera Film | false | false |
| 20 | 19 | The White Sound 2010 Re-release | $15,558 | -7.3% | 6 | - | $2,593 | $280,807 | 7 | Camera Film | false | false |
| 21 | 21 | The Imaginarium of Doctor Parnassus | $10,327 | +0.3% | 7 | +1 | $1,475 | $710,649 | 10 | Sony Pictures Releasing | false | false |
