| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $3,767,803 | -27.3% | 402 | -148 | $9,372 | $80,279,176 | 6 | 20th Century Fox International | false | false |
| 2 | - | The Wolfman | $2,705,868 | - | 391 | - | $6,920 | $2,705,868 | 1 | United International Pictures | true | false |
| 3 | 2 | Sorry If I Want to Marry You | $1,977,561 | -50.7% | 469 | -23 | $4,216 | $7,690,494 | 2 | Medusa Distribuzione | false | false |
| 4 | - | The Youngest Son | $1,305,765 | - | 320 | - | $4,080 | $1,305,765 | 1 | Medusa Distribuzione | true | false |
| 5 | - | Did You Hear About the Morgans? | $1,106,186 | - | 232 | - | $4,768 | $1,106,186 | 1 | Sony Pictures Releasing | true | false |
| 6 | 6 | Alvin and the Chipmunks: The Squeakquel | $591,942 | -39.6% | 229 | -87 | $2,584 | $7,496,052 | 4 | 20th Century Fox International | false | false |
| 7 | - | Le missionnaire | $546,995 | - | 173 | - | $3,161 | $546,995 | 1 | Eagle Pictures | true | false |
| 8 | 8 | The Concert | $521,105 | -21.1% | 128 | -11 | $4,071 | $2,403,608 | 3 | BIM Distribuzione | false | false |
| 9 | 5 | The Lovely Bones | $460,730 | -60.1% | 253 | -79 | $1,821 | $2,086,600 | 2 | United International Pictures | false | false |
| 10 | 4 | Kiss Me Again | $393,619 | -67% | 191 | -185 | $2,060 | $12,108,854 | 4 | Medusa Distribuzione | false | false |
| 11 | 3 | Paranormal Activity | $314,911 | -77.7% | 202 | -198 | $1,558 | $8,816,354 | 3 | Filmauro | false | false |
| 12 | 10 | Lilly the Witch: The Dragon and the Magic Book | $293,531 | -27.5% | 137 | -18 | $2,142 | $856,513 | 2 | Walt Disney Pictures | false | false |
| 13 | 7 | Up in the Air | $282,504 | -59% | 99 | -90 | $2,853 | $7,374,809 | 5 | United International Pictures | false | false |
| 14 | 9 | The First Beautiful Thing | $235,079 | -46.3% | 68 | -58 | $3,457 | $8,326,036 | 6 | Medusa Distribuzione | false | false |
| 15 | 12 | The Man Who Will Come | $92,827 | -37.9% | 38 | -15 | $2,442 | $1,279,878 | 5 | Mikado Film | false | false |
| 16 | 11 | Lourdes | $81,459 | -49.8% | 64 | -19 | $1,272 | $339,085 | 2 | N/A | false | false |
| 17 | - | Call of the Wild | $69,218 | - | 62 | - | $1,116 | $69,218 | 1 | N/A | true | false |
| 18 | 15 | An Education | $67,323 | -33.8% | 24 | -13 | $2,805 | $381,877 | 3 | Sony Pictures Releasing | false | false |
| 19 | 17 | Soul Kitchen | $55,829 | -35.2% | 18 | -11 | $3,101 | $2,185,307 | 7 | BIM Distribuzione | false | false |
| 20 | - | The Mouth of the Wolf | $40,382 | - | 7 | - | $5,768 | $40,382 | 1 | BIM Distribuzione | true | false |
| 21 | 16 | A Single Man | $39,647 | -54.3% | 14 | -21 | $2,831 | $1,382,237 | 6 | N/A | false | false |
| 22 | 14 | Me, Them and Lara | $24,734 | -75.7% | 12 | -32 | $2,061 | $21,900,635 | 7 | Warner Bros. | false | false |
| 23 | 19 | The Hedgehog | $20,643 | -27.1% | 11 | -3 | $1,876 | $3,236,371 | 7 | Eagle Pictures | false | false |
| 24 | 21 | Pet Pals: Marco Polo's Code | $13,283 | -36.9% | 25 | -25 | $531 | $981,737 | 5 | 01 Distribution | false | false |
| 25 | 23 | Cloudy with a Chance of Meatballs | $9,958 | +2.9% | 46 | +8 | $216 | $8,244,378 | 9 | Sony Pictures Releasing | false | false |
