| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $324,046 | -18.9% | 67 | -12 | $4,836 | $12,365,759 | 10 | 20th Century Fox International | false | false |
| 2 | 2 | The Wolfman | $200,659 | -20.3% | 92 | -4 | $2,181 | $556,293 | 2 | United International Pictures | false | false |
| 3 | 3 | Percy Jackson & the Olympians: The Lightning Thief | $153,514 | -30% | 84 | -5 | $1,827 | $438,444 | 2 | 20th Century Fox International | false | false |
| 4 | - | Toy Story 2009 Re-release | $140,663 | - | 37 | - | $3,801 | $140,663 | 1 | Walt Disney Pictures | true | false |
| 5 | 4 | Valentine's Day | $80,589 | -23% | 42 | - | $1,918 | $224,148 | 2 | Warner Bros. | false | false |
| 6 | 5 | Tooth Fairy | $73,066 | -13% | 50 | +1 | $1,461 | $867,622 | 5 | 20th Century Fox International | false | false |
| 7 | - | Precious | $56,120 | - | 20 | - | $2,806 | $56,120 | 1 | Cine Colombia | true | false |
| 8 | - | Cirque du Freak: The Vampire's Assistant | $46,096 | - | 38 | - | $1,213 | $46,096 | 1 | United International Pictures | true | false |
| 9 | 6 | Invictus | $40,241 | -31% | 26 | -6 | $1,547 | $246,751 | 3 | Warner Bros. | false | false |
| 10 | 7 | Old Dogs | $39,371 | -16.6% | 45 | +1 | $874 | $1,047,205 | 7 | Walt Disney Pictures | false | false |
| 11 | - | The Lovely Bones | $36,371 | - | 26 | - | $1,398 | $36,371 | 1 | United International Pictures | true | false |
| 12 | 8 | The Hurt Locker | $19,092 | -35.8% | 11 | -2 | $1,735 | $61,202 | 2 | Cineplex | false | false |
| 13 | 10 | Up in the Air | $14,451 | -9.5% | 17 | - | $850 | $223,869 | 5 | United International Pictures | false | false |
| 14 | - | An Education | $12,869 | - | 6 | - | $2,144 | $12,869 | 1 | Sony Pictures Releasing | true | false |
| 15 | 13 | Alvin and the Chipmunks: The Squeakquel | $8,576 | -31.5% | 32 | -12 | $268 | $1,346,626 | 8 | 20th Century Fox International | false | false |
| 16 | 9 | Sherlock Holmes | $6,003 | -71.4% | 8 | -19 | $750 | $1,653,646 | 7 | Warner Bros. | false | false |
| 17 | 11 | Nine | $5,261 | -64.4% | 8 | -1 | $657 | $114,707 | 4 | Sony Pictures Releasing | false | false |
| 18 | 15 | The Princess and the Frog | $5,229 | -25.4% | 25 | -6 | $209 | $1,813,236 | 9 | Walt Disney Pictures | false | false |
| 19 | 16 | Ninja Assassin | $4,705 | +87.9% | 8 | +3 | $588 | $126,557 | 4 | Warner Bros. | false | false |
| 20 | 12 | Broken Embraces | $3,061 | -77.9% | 8 | -6 | $382 | $77,659 | 3 | United International Pictures | false | false |
| 21 | 20 | The Stepfather | $2,785 | +410.1% | 3 | +2 | $928 | $93,726 | 11 | Sony Pictures Releasing | false | false |
| 22 | 17 | Zombieland | $1,722 | -28.7% | 4 | -4 | $430 | $160,980 | 6 | Sony Pictures Releasing | false | false |
| 23 | 18 | Astro Boy | $1,614 | -32.9% | 9 | -2 | $179 | $70,887 | 6 | Cine Colombia | false | false |
| 24 | 14 | Departures | $977 | -86.1% | 3 | -1 | $325 | $100,263 | 6 | Cine Colombia | false | false |
