| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 3 | Avatar | $55,754 | +10.8% | 11 | - | $5,068 | $1,105,978 | 8 | 20th Century Fox International | false | false |
| 2 | 1 | The Princess and the Frog | $40,033 | -32% | 8 | - | $5,004 | $118,415 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 4 | Zero 2 | $27,006 | -38.3% | 9 | - | $3,000 | $220,349 | 3 | N/A | false | false |
| 4 | 2 | Nasha Russia. Yaytsa sudby | $23,287 | -57.2% | 5 | - | $4,657 | $93,124 | 2 | ACME | false | false |
| 5 | - | From Paris with Love | $16,503 | - | 5 | - | $3,300 | $16,503 | 1 | ACME | true | false |
| 6 | - | Did You Hear About the Morgans? | $15,080 | - | 6 | - | $2,513 | $17,125 | 1 | Sony Pictures Releasing | true | false |
| 7 | 5 | Up in the Air | $11,122 | -32.9% | 6 | +5 | $1,853 | $39,781 | 3 | Universal Pictures International (UPI) | false | false |
| 8 | 6 | The Book of Eli | $6,176 | -43.8% | 6 | - | $1,029 | $54,151 | 3 | Sony Pictures Releasing | false | false |
| 9 | 7 | It's Complicated | $5,508 | -41.2% | 6 | - | $918 | $90,237 | 4 | Universal Pictures International (UPI) | false | false |
| 10 | - | Pope Joan | $4,941 | - | 2 | - | $2,470 | $4,941 | 1 | ACME | true | false |
| 11 | 8 | Alvin and the Chipmunks: The Squeakquel | $3,005 | -46.1% | 10 | - | $300 | $297,158 | 7 | Universal Pictures International (UPI) | false | false |
| 12 | 9 | Sherlock Holmes | $1,335 | -73.4% | 4 | -3 | $333 | $235,780 | 6 | - | false | false |
| 13 | 10 | The Imaginarium of Doctor Parnassus | $886 | -55.8% | 2 | -1 | $443 | $44,427 | 5 | ACME | false | false |
| 14 | 13 | The World is Big and Salvation Lurks Around the Corner | $742 | -6.1% | 1 | - | $742 | $18,969 | 15 | N/A | false | false |
| 15 | 15 | In the Loop | $342 | -27.2% | 1 | - | $342 | $3,593 | 4 | N/A | false | false |
| 16 | 11 | Ninja Assassin | $218 | -82.5% | 3 | -3 | $72 | $30,354 | 4 | - | false | false |
| 17 | - | The Flight Before Christmas | $206 | - | 2 | - | $103 | $27,955 | 13 | Universal Pictures International (UPI) | false | false |
| 18 | 16 | Looking for Eric | $155 | -48.2% | 1 | - | $155 | $2,763 | 7 | N/A | false | false |
| 19 | 18 | Golden Door 2010 Re-release | $116 | -11.5% | 1 | - | $116 | $1,895 | 5 | N/A | false | false |
| 20 | - | Up | $59 | - | 1 | - | $59 | $412,356 | 25 | Universal Pictures International (UPI) | false | false |
