| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $1,461,286 | -31% | 451 | -23 | $3,240 | $43,961,377 | 8 | 20th Century Fox International | false | false |
| 2 | - | The Final Destination | $986,023 | - | 239 | - | $4,125 | $1,702,327 | 1 | PlayArte Pictures | true | false |
| 3 | 2 | Alvin and the Chipmunks: The Squeakquel | $666,090 | -43.2% | 365 | -13 | $1,824 | $18,356,209 | 5 | 20th Century Fox International | false | false |
| 4 | 3 | Sherlock Holmes | $478,161 | -41.7% | 305 | -6 | $1,567 | $10,521,686 | 5 | Warner Bros. | false | false |
| 5 | 6 | Up in the Air | $426,330 | -25.5% | 164 | -1 | $2,599 | $2,832,255 | 3 | Paramount Pictures International | false | false |
| 6 | 5 | Edge of Darkness | $388,010 | -37.7% | 155 | +1 | $2,503 | $1,340,566 | 2 | N/A | false | false |
| 7 | 4 | Tooth Fairy | $387,599 | -39% | 174 | +1 | $2,227 | $3,326,497 | 3 | 20th Century Fox International | false | false |
| 8 | - | High School Musical: O Desafio | $346,846 | - | 203 | - | $1,708 | $346,846 | 1 | Walt Disney Pictures | true | false |
| 9 | 7 | Invictus | $255,099 | -16.2% | 78 | +2 | $3,270 | $749,854 | 2 | Warner Bros. | false | false |
| 10 | - | The Hurt Locker | $125,910 | - | 43 | - | $2,928 | $125,910 | 1 | N/A | true | false |
| 11 | 8 | Nine | $84,514 | -48.2% | 40 | - | $2,112 | $330,660 | 2 | Sony Pictures Releasing | false | false |
| 12 | 9 | Xuxa and the Mystery of the Little Ugly Princess | $64,419 | -55% | 195 | -5 | $330 | $4,066,234 | 7 | PlayArte Pictures | false | false |
| 13 | - | Ninja Assassin | $54,824 | - | 44 | - | $1,246 | $54,824 | 1 | Warner Bros. | true | false |
| 14 | 10 | Zombieland | $47,355 | -60.9% | 39 | -8 | $1,214 | $216,277 | 2 | Sony Pictures Releasing | false | false |
| 15 | 19 | Where the Wild Things Are | $21,652 | -15.9% | 17 | - | $1,273 | $337,914 | 4 | Warner Bros. | false | false |
| 16 | 18 | The Fourth Kind | $20,983 | -19.6% | 37 | -5 | $567 | $839,278 | 6 | N/A | false | false |
| 17 | 11 | Astro Boy | $20,264 | -71.4% | 60 | -16 | $337 | $443,185 | 3 | Paris Filmes | false | false |
| 18 | 29 | Management | $17,237 | +205.3% | 19 | +11 | $907 | $458,311 | 9 | N/A | false | false |
| 19 | 13 | Hachi: A Dog's Tale | $15,931 | -54% | 78 | -20 | $204 | $3,470,917 | 7 | N/A | false | false |
| 20 | 14 | Bad Lieutenant: Port of Call New Orleans | $15,685 | -51.7% | 39 | -7 | $402 | $609,997 | 4 | N/A | false | false |
| 21 | 12 | Lula, the Son of Brazil | $15,328 | -76.5% | 69 | -59 | $222 | $3,743,466 | 6 | Europa Filmes | false | false |
| 22 | 15 | The Princess and the Frog | $10,869 | -63.3% | 52 | -43 | $209 | $3,779,516 | 9 | Walt Disney Pictures | false | false |
| 23 | 22 | Julie & Julia | $10,234 | -28.2% | 22 | +1 | $465 | $1,193,131 | 11 | Sony Pictures Releasing | false | false |
| 24 | 16 | Chéri | $10,021 | -65.7% | 10 | -11 | $1,002 | $173,073 | 3 | N/A | false | false |
| 25 | 20 | Broken Embraces | $7,140 | -67.9% | 23 | -9 | $310 | $1,341,131 | 10 | Universal Pictures International (UPI) | false | false |
| 26 | 21 | 2012 | $6,438 | -67.2% | 17 | -12 | $378 | $25,643,973 | 13 | Sony Pictures Releasing | false | false |
| 27 | 27 | Easy Virtue | $6,322 | -2.4% | 5 | +2 | $1,264 | $165,764 | 16 | Sony Pictures Releasing | false | false |
| 28 | 17 | Couples Retreat | $4,789 | -83.3% | 25 | -39 | $191 | $3,465,795 | 7 | Universal Pictures International (UPI) | false | false |
| 29 | 23 | The Twilight Saga: New Moon | $3,127 | -76.9% | 12 | -15 | $260 | $25,920,837 | 12 | Paris Filmes | false | false |
| 30 | 25 | Wild Grass | $2,740 | -74.2% | 7 | -3 | $391 | $192,307 | 4 | N/A | false | false |
| 31 | 26 | Paranormal Activity | $2,728 | -59.8% | 19 | -14 | $143 | $4,895,433 | 10 | PlayArte Pictures | false | false |
| 32 | 24 | Coco Before Chanel | $2,364 | -77.8% | 10 | -6 | $236 | $852,389 | 15 | Warner Bros. | false | false |
| 33 | 35 | A Christmas Carol | $1,036 | +568.4% | 6 | +4 | $172 | $2,921,935 | 14 | Walt Disney Pictures | false | false |
| 34 | - | The Assailant | $595 | - | 4 | - | $148 | $2,019,000 | 15 | Walt Disney Pictures | false | false |
| 35 | 34 | Saw VI | $168 | -68.8% | 1 | -2 | $168 | $1,732,786 | 14 | Walt Disney Pictures | false | false |
| 36 | - | Up | $16 | - | 2 | - | $8 | $10,528,510 | 23 | Walt Disney Pictures | false | false |
