| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $568,585 | -12.5% | 19 | - | $29,925 | $9,264,145 | 5 | 20th Century Fox International | false | false |
| 2 | 2 | Sherlock Holmes | $116,484 | -26.5% | 21 | +2 | $5,546 | $2,086,101 | 4 | Warner Bros. | false | false |
| 3 | - | The Men Who Stare at Goats | $52,060 | - | 9 | - | $5,784 | $67,809 | 1 | N/A | true | false |
| 4 | 3 | Bodyguards and Assassins | $43,364 | -38.2% | 17 | +1 | $2,550 | $1,022,355 | 4 | N/A | false | false |
| 5 | - | Invictus | $42,224 | - | 16 | - | $2,639 | $53,844 | 1 | Warner Bros. | true | false |
| 6 | 4 | Hachi: A Dog's Tale | $27,007 | -40.5% | 14 | - | $1,929 | $121,237 | 2 | 20th Century Fox International | false | false |
| 7 | 9 | Broken Embraces | $11,342 | -25.9% | 5 | - | $2,268 | $44,690 | 2 | N/A | false | false |
| 8 | 5 | Bad Lieutenant: Port of Call New Orleans | $10,016 | -67.8% | 7 | -1 | $1,430 | $69,027 | 2 | N/A | false | false |
| 9 | - | Air Doll | $8,379 | - | 3 | - | $2,793 | $11,089 | 1 | N/A | true | false |
| 10 | 6 | Couples Retreat | $8,053 | -64.2% | 7 | -7 | $1,150 | $195,781 | 3 | United International Pictures | false | false |
| 11 | 7 | The Box | $6,608 | -69.1% | 10 | - | $660 | $49,266 | 2 | N/A | false | false |
| 12 | - | 20th Century Boys 3: Redemption | $6,585 | - | 6 | - | $1,097 | $8,718 | 1 | N/A | true | false |
| 13 | 8 | The Treasure Hunter | $5,992 | -63% | 6 | -7 | $998 | $213,181 | 3 | N/A | false | false |
| 14 | 11 | New York, I Love You | $3,774 | -40.8% | 2 | - | $1,887 | $110,483 | 4 | N/A | false | false |
| 15 | 10 | Mulan: Rise of a Warrior | $3,014 | -64.5% | 6 | -4 | $502 | $22,162 | 2 | N/A | false | false |
| 16 | 12 | The Private Lives of Pippa Lee | $717 | -65.5% | 1 | -1 | $717 | $28,510 | 3 | N/A | false | false |
| 17 | 14 | Ex | $442 | -60.3% | 1 | - | $442 | $16,700 | 4 | N/A | false | false |
