| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $2,779,199 | -34.4% | 480 | -658 | $5,789 | $28,039,076 | 4 | 20th Century Fox International | false | false |
| 2 | 2 | Sherlock Holmes | $1,816,936 | -45.2% | 638 | -45 | $2,847 | $6,869,456 | 2 | Warner Bros. | false | false |
| 3 | 3 | Alvin and the Chipmunks: The Squeakquel | $921,481 | -53.5% | 456 | -13 | $2,020 | $8,266,345 | 3 | 20th Century Fox International | false | false |
| 4 | 4 | Paranormal Activity | $547,655 | -39% | 349 | -11 | $1,569 | $4,237,938 | 3 | Gussi Films | false | false |
| 5 | - | Law Abiding Citizen | $486,155 | - | 252 | - | $1,929 | $493,104 | 1 | N/A | true | false |
| 6 | - | Zombieland | $284,448 | - | 200 | - | $1,422 | $284,448 | 1 | Sony Pictures Releasing | true | false |
| 7 | 5 | The Princess and the Frog | $256,882 | -52.1% | 328 | -99 | $783 | $5,708,907 | 5 | Walt Disney Pictures | false | false |
| 8 | - | Labor Pains | $228,510 | - | 182 | - | $1,255 | $228,510 | 1 | N/A | true | false |
| 9 | 13 | The Box | $154,127 | +55.6% | 157 | +51 | $981 | $1,033,010 | 5 | Videocine | false | false |
| 10 | 24 | The Stepfather | $101,941 | +6,044.7% | 108 | +107 | $943 | $315,706 | 5 | Sony Pictures Releasing | false | false |
| 11 | 7 | Old Dogs | $101,540 | -57.3% | 126 | -88 | $805 | $4,901,680 | 7 | Walt Disney Pictures | false | false |
| 12 | 8 | Everybody's Fine | $100,747 | -37.5% | 81 | -59 | $1,243 | $908,602 | 3 | Walt Disney Pictures | false | false |
| 13 | 6 | All About Steve | $99,152 | -58.6% | 124 | -29 | $799 | $499,141 | 2 | 20th Century Fox International | false | false |
| 14 | - | Mutant Chronicles | $97,178 | - | 130 | - | $747 | $97,178 | 1 | Videocine | true | false |
| 15 | 12 | Case 39 | $56,233 | -46.6% | 71 | -31 | $792 | $2,897,682 | 6 | Paramount Pictures International | false | false |
| 16 | 9 | Nikté | $34,819 | -70.9% | 150 | -221 | $232 | $1,252,656 | 4 | Universal Pictures International (UPI) | false | false |
| 17 | 10 | The Twilight Saga: New Moon | $34,484 | -69.6% | 94 | -96 | $366 | $18,777,454 | 8 | N/A | false | false |
| 18 | 11 | 2012 | $28,492 | -74.9% | 91 | -87 | $313 | $19,396,186 | 9 | Sony Pictures Releasing | false | false |
| 19 | - | Opium: Diary of a Madwoman | $13,994 | - | 9 | - | $1,554 | $13,994 | 1 | N/A | true | false |
| 20 | 15 | New York, I Love You | $9,285 | -56.7% | 6 | -18 | $1,547 | $271,415 | 4 | N/A | false | false |
| 21 | 14 | Planet 51 | $7,590 | -82% | 37 | -90 | $205 | $4,585,429 | 7 | Videocine | false | false |
| 22 | 20 | The Haunting | $5,003 | +50.8% | 7 | +1 | $714 | $344,079 | 8 | N/A | false | false |
| 23 | 17 | Lemon Tree | $4,592 | -35.9% | 3 | -6 | $1,530 | $38,230 | 3 | N/A | false | false |
| 24 | 16 | Julie & Julia | $4,009 | -60.8% | 6 | -10 | $668 | $493,153 | 12 | Sony Pictures Releasing | false | false |
| 25 | 18 | Easy Virtue | $2,910 | -43.8% | 6 | -3 | $485 | $61,452 | 6 | Sony Pictures Releasing | false | false |
| 26 | 21 | Paris | $2,300 | -22.1% | 4 | -1 | $575 | $57,644 | 5 | N/A | false | false |
| 27 | 22 | Away We Go | $1,030 | -47.8% | 3 | +1 | $343 | $74,986 | 8 | Universal Pictures International (UPI) | false | false |
| 28 | 27 | Taking Woodstock | $642 | +13.8% | 2 | -1 | $321 | $30,530 | 6 | Universal Pictures International (UPI) | false | false |
| 29 | 29 | Year One | $224 | +7.2% | 2 | +1 | $112 | $1,097,413 | 14 | Sony Pictures Releasing | false | false |
