| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Avatar | $2,777,505 | -11.8% | 595 | -18 | $4,668 | $33,548,579 | 5 | 20th Century Fox International | false | false |
| 2 | 1 | Alvin and the Chipmunks: The Squeakquel | $2,503,069 | -26.3% | 414 | +19 | $6,046 | $10,764,845 | 2 | 20th Century Fox International | false | false |
| 3 | 3 | Sherlock Holmes | $1,775,019 | -23.8% | 318 | -24 | $5,581 | $5,769,672 | 2 | Warner Bros. | false | false |
| 4 | 4 | Lula, the Son of Brazil | $331,500 | -40.9% | 283 | -63 | $1,171 | $3,446,805 | 3 | Europa Filmes | false | false |
| 5 | 7 | Xuxa and the Mystery of the Little Ugly Princess | $287,550 | -8.8% | 209 | +3 | $1,375 | $3,140,800 | 4 | PlayArte Pictures | false | false |
| 6 | - | Bad Lieutenant: Port of Call New Orleans | $241,387 | - | 72 | - | $3,352 | $241,387 | 1 | N/A | true | false |
| 7 | 5 | Couples Retreat | $199,553 | -43.9% | 135 | -25 | $1,478 | $3,312,065 | 4 | Universal Pictures International (UPI) | false | false |
| 8 | 6 | Hachi: A Dog's Tale | $167,967 | -47.1% | 125 | -26 | $1,343 | $3,298,593 | 4 | N/A | false | false |
| 9 | - | Where the Wild Things Are | $108,429 | - | 24 | - | $4,517 | $108,429 | 1 | Warner Bros. | true | false |
| 10 | 11 | The Princess and the Frog | $74,954 | -19.5% | 177 | +13 | $423 | $3,752,305 | 6 | Walt Disney Pictures | false | false |
| 11 | 8 | The Twilight Saga: New Moon | $73,631 | -44.5% | 93 | -43 | $791 | $27,254,625 | 9 | Paris Filmes | false | false |
| 12 | 10 | 2012 | $67,359 | -45.7% | 69 | -39 | $976 | $25,498,414 | 10 | Sony Pictures Releasing | false | false |
| 13 | 9 | The Fourth Kind | $49,618 | -60.1% | 45 | -20 | $1,102 | $737,400 | 3 | N/A | false | false |
| 14 | - | The Great Buck Howard | $45,634 | - | 15 | - | $3,042 | $45,634 | 1 | Europa Filmes | true | false |
| 15 | 13 | New York, I Love You | $38,662 | +19% | 20 | +8 | $1,933 | $436,040 | 5 | N/A | false | false |
| 16 | 12 | Broken Embraces | $35,330 | -12.1% | 25 | +1 | $1,413 | $1,293,451 | 7 | Universal Pictures International (UPI) | false | false |
| 17 | - | Motherhood | $35,178 | - | 20 | - | $1,758 | $35,178 | 1 | Paris Filmes | true | false |
| 18 | - | Wild Grass | $26,169 | - | 9 | - | $2,907 | $135,305 | 1 | N/A | true | false |
| 19 | 18 | Julie & Julia | $21,453 | +120.1% | 19 | +6 | $1,129 | $1,107,768 | 8 | Sony Pictures Releasing | false | false |
| 20 | 15 | Easy Virtue | $16,449 | -15.3% | 4 | +1 | $4,112 | $130,826 | 13 | Sony Pictures Releasing | false | false |
| 21 | 14 | Paranormal Activity | $12,247 | -50.6% | 43 | -10 | $284 | $5,142,474 | 7 | PlayArte Pictures | false | false |
| 22 | 19 | 500 Days of Summer | $8,568 | +2.4% | 11 | +2 | $778 | $1,248,007 | 11 | 20th Century Fox International | false | false |
| 23 | 17 | Inglourious Basterds | $8,325 | -29.4% | 10 | -1 | $832 | $5,023,841 | 15 | Universal Pictures International (UPI) | false | false |
| 24 | 27 | The Private Lives of Pippa Lee | $6,206 | +547.8% | 5 | -1 | $1,241 | $73,546 | 5 | PlayArte Pictures | false | false |
| 25 | 21 | Planet 51 | $6,076 | +6.7% | 33 | -11 | $184 | $2,219,596 | 8 | N/A | false | false |
| 26 | 20 | Coco Before Chanel | $5,756 | -13.3% | 6 | -1 | $959 | $831,885 | 12 | Warner Bros. | false | false |
| 27 | 16 | The Edge of Love | $3,836 | -77.3% | 7 | -1 | $548 | $28,338 | 2 | N/A | false | false |
| 28 | 22 | Smoke Gets in Your Eyes | $3,039 | -41.7% | 10 | - | $303 | $197,319 | 7 | PlayArte Pictures | false | false |
| 29 | 26 | The Soloist | $2,322 | +95.3% | 6 | - | $387 | $255,736 | 11 | Universal Pictures International (UPI) | false | false |
| 30 | 24 | A Christmas Carol | $1,443 | -35.2% | 10 | -3 | $144 | $3,089,714 | 11 | Walt Disney Pictures | false | false |
| 31 | 25 | Saw VI | $883 | -34.6% | 4 | -1 | $220 | $1,832,726 | 11 | Walt Disney Pictures | false | false |
| 32 | 32 | The Assailant | $577 | +630.4% | 2 | -1 | $288 | $2,136,197 | 12 | Walt Disney Pictures | false | false |
| 33 | 28 | Cloudy with a Chance of Meatballs | $403 | -55.8% | 4 | -4 | $100 | $7,800,285 | 16 | Sony Pictures Releasing | false | false |
| 34 | 30 | Surrogates | $103 | -59.9% | 1 | -2 | $103 | $1,838,881 | 13 | Walt Disney Pictures | false | false |
