| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $7,714,637 | -11.1% | 506 | -74 | $15,246 | $58,510,427 | 4 | 20th Century Fox International | false | false |
| 2 | - | It's Complicated | $3,100,750 | - | 304 | - | $10,199 | $3,163,900 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 2 | Sherlock Holmes | $2,463,457 | -41.2% | 307 | -1 | $8,024 | $16,419,720 | 3 | Roadshow Films | false | false |
| 4 | 3 | Alvin and the Chipmunks: The Squeakquel | $2,125,336 | -28.9% | 345 | -20 | $6,160 | $15,015,137 | 3 | 20th Century Fox International | false | false |
| 5 | 4 | Old Dogs | $1,189,274 | -28.8% | 255 | -16 | $4,663 | $6,469,136 | 3 | Walt Disney Pictures | false | false |
| 6 | 7 | The Princess and the Frog | $1,012,628 | -2.8% | 225 | -4 | $4,500 | $3,090,341 | 2 | Walt Disney Pictures | false | false |
| 7 | 5 | The Lovely Bones | $931,286 | -33.9% | 178 | - | $5,231 | $3,936,177 | 3 | Paramount Pictures International | false | false |
| 8 | 8 | Fantastic Mr. Fox | $613,319 | +2.2% | 222 | +1 | $2,762 | $1,866,701 | 8 | 20th Century Fox International | false | false |
| 9 | 6 | Did You Hear About the Morgans? | $585,325 | -53.3% | 208 | - | $2,814 | $4,882,270 | 3 | Sony Pictures Releasing | false | false |
| 10 | 9 | Bright Star | $262,879 | -43.6% | 66 | +1 | $3,983 | $1,778,050 | 3 | Hopscotch Films | false | false |
| 11 | 10 | The Twilight Saga: New Moon | $200,211 | -44.7% | 124 | -72 | $1,614 | $35,000,118 | 8 | - | false | false |
| 12 | 12 | Nowhere Boy | $96,151 | -40.7% | 34 | +1 | $2,827 | $621,981 | 3 | Icon Film Distribution | false | false |
| 13 | 11 | 3 Idiots | $80,448 | -64.7% | 18 | -2 | $4,469 | $925,863 | 3 | Mind Blowing Films | false | false |
| 14 | 16 | Broken Embraces | $71,884 | -44.3% | 23 | - | $3,125 | $605,408 | 4 | Paramount Pictures International | false | false |
| 15 | 15 | Cloudy with a Chance of Meatballs | $57,484 | -57.2% | 63 | -141 | $912 | $7,409,255 | 7 | Sony Pictures Releasing | false | false |
| 16 | 14 | Where the Wild Things Are | $54,174 | -61.4% | 52 | -156 | $1,041 | $5,693,853 | 6 | Roadshow Films | false | false |
| 17 | 13 | Paranormal Activity | $43,404 | -71.5% | 61 | -114 | $711 | $7,818,643 | 6 | Icon Film Distribution | false | false |
| 18 | 19 | Mao's Last Dancer | $37,445 | -26.8% | 26 | -12 | $1,440 | $14,008,032 | 15 | Roadshow Films | false | false |
| 19 | 17 | Planet 51 | $32,486 | -63% | 46 | -124 | $706 | $2,581,551 | 5 | Hoyts Distribution | false | false |
| 20 | - | Dinosaurs Alive | $31,737 | - | 2 | - | $15,868 | $606,524 | 20 | IMAX | false | false |
| 21 | - | Dulha Mil Gaya | $20,420 | - | 5 | - | $4,084 | $20,420 | 1 | Saini Enterprises | true | false |
| 22 | - | Pyaar Impossible | $20,082 | - | 8 | - | $2,510 | $20,082 | 1 | Mind Blowing Films | true | false |
| 23 | - | Mitti | $6,103 | - | 4 | - | $1,525 | $6,103 | 1 | Eros Worldwide | true | false |
