| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Natale a Beverly Hills | $13,016,621 | +161.4% | 621 | +14 | $20,960 | $20,298,484 | 2 | Filmauro | false | false |
| 2 | 2 | Me and Marilyn | $7,103,773 | +200.9% | 563 | +5 | $12,617 | $10,535,164 | 2 | Medusa Distribuzione | false | false |
| 3 | - | Sherlock Holmes | $6,536,572 | - | 394 | - | $16,590 | $6,536,739 | 1 | Warner Bros. | true | false |
| 4 | 4 | The Princess and the Frog | $3,829,420 | +143.8% | 446 | +8 | $8,586 | $6,229,136 | 2 | Walt Disney Pictures | false | false |
| 5 | 3 | A Christmas Carol | $2,847,612 | +55.7% | 267 | -103 | $10,665 | $19,734,329 | 4 | Walt Disney Pictures | false | false |
| 6 | - | Cloudy with a Chance of Meatballs | $2,330,309 | - | 289 | - | $8,063 | $2,577,224 | 1 | Sony Pictures Releasing | true | false |
| 7 | - | Brothers | $1,268,181 | - | 201 | - | $6,309 | $1,371,529 | 1 | 01 Distribution | true | false |
| 8 | 5 | Cado dalle nubi | $862,371 | +2.6% | 119 | -126 | $7,246 | $17,927,044 | 5 | Medusa Distribuzione | false | false |
| 9 | - | Amelia | $767,376 | - | 177 | - | $4,335 | $819,254 | 1 | 20th Century Fox International | true | false |
| 10 | 8 | A Serious Man | $268,521 | +24.5% | 46 | -63 | $5,837 | $3,269,075 | 4 | Medusa Distribuzione | false | false |
| 11 | 7 | Astro Boy | $262,685 | +6.6% | 183 | -33 | $1,435 | $593,768 | 2 | Eagle Pictures | false | false |
| 12 | 9 | Looking for Eric | $252,944 | +96.6% | 63 | -11 | $4,014 | $1,130,979 | 4 | BIM Distribuzione | false | false |
| 13 | 14 | Welcome | $202,258 | +231.3% | 40 | +23 | $5,056 | $414,393 | 3 | Teodora Film | false | false |
| 14 | 6 | Dorian Gray | $178,678 | -50.5% | 39 | -128 | $4,581 | $8,423,183 | 5 | Eagle Pictures | false | false |
| 15 | 10 | The Cézanne Affair/The Man Who Will Come | $119,402 | -4% | 23 | -59 | $5,191 | $2,045,921 | 4 | 01 Distribution | false | false |
| 16 | 17 | Broken Embraces | $41,550 | +16.3% | 14 | -14 | $2,967 | $5,312,512 | 7 | Warner Bros. | false | false |
| 17 | 20 | The Wedding Song | $24,439 | +41.3% | 11 | - | $2,221 | $50,401 | 2 | N/A | false | false |
| 18 | 29 | Whatever Works | $15,538 | +173.3% | 4 | -3 | $3,884 | $7,754,554 | 15 | Medusa Distribuzione | false | false |
| 19 | 18 | Planet 51 | $15,432 | -47% | 25 | -24 | $617 | $3,667,046 | 6 | N/A | false | false |
| 20 | 24 | Moon | $15,042 | +38.5% | 5 | -2 | $3,008 | $89,207 | 4 | Sony Pictures Releasing | false | false |
| 21 | 21 | The Men Who Stare at Goats | $13,547 | +11.1% | 8 | -2 | $1,693 | $5,577,762 | 8 | Medusa Distribuzione | false | false |
| 22 | 19 | The Twilight Saga: New Moon | $13,042 | -26.4% | 8 | -12 | $1,630 | $24,765,695 | 6 | Eagle Pictures | false | false |
| 23 | 13 | The Ugly Truth | $10,730 | -86.8% | 3 | -49 | $3,576 | $3,200,205 | 5 | Sony Pictures Releasing | false | false |
| 24 | 27 | The White Ribbon | $8,810 | +4.1% | 2 | -4 | $4,405 | $815,851 | 9 | Lucky Red | false | false |
| 25 | 15 | 2012 | $7,100 | -84.7% | 8 | -43 | $887 | $21,080,952 | 7 | Sony Pictures Releasing | false | false |
| 26 | 28 | Baaria | $6,890 | -2.4% | 2 | -6 | $3,445 | $15,885,457 | 14 | Medusa Distribuzione | false | false |
| 27 | 23 | Public Enemies | $6,569 | -39.6% | 3 | -6 | $2,189 | $8,491,750 | 8 | United International Pictures | false | false |
| 28 | - | Up | $5,379 | - | 6 | - | $896 | $23,770,598 | 11 | Walt Disney Pictures | false | false |
| 29 | 32 | The Imaginarium of Doctor Parnassus | $4,962 | +45.5% | 3 | -2 | $1,654 | $11,119,996 | 10 | N/A | false | false |
| 30 | 26 | Tetro | $3,659 | -60.6% | 2 | -8 | $1,829 | $631,756 | 6 | BIM Distribuzione | false | false |
| 31 | 37 | Julie & Julia | $3,601 | +372.6% | 8 | -2 | $450 | $3,006,094 | 10 | Sony Pictures Releasing | false | false |
| 32 | 33 | Valentino: The Last Emperor | $3,541 | +32.5% | 1 | - | $3,541 | $211,275 | 6 | Medusa Distribuzione | false | false |
| 33 | 12 | Couples Retreat | $2,461 | -97% | 1 | -73 | $2,461 | $2,115,759 | 4 | United International Pictures | false | false |
| 34 | 34 | Inglourious Basterds | $2,143 | -4.4% | 1 | -3 | $2,143 | $14,058,662 | 13 | United International Pictures | false | false |
