| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $12,667,033 | +15.3% | 800 | +3 | $15,833 | $29,154,824 | 2 | 20th Century Fox International | false | false |
| 2 | - | Alvin and the Chipmunks: The Squeakquel | $3,390,261 | - | 352 | - | $9,631 | $3,390,261 | 1 | 20th Century Fox International | true | false |
| 3 | - | It's Complicated | $2,195,991 | - | 219 | - | $10,027 | $2,195,991 | 1 | United International Pictures | true | false |
| 4 | - | Zombieland | $1,416,011 | - | 250 | - | $5,664 | $1,416,011 | 1 | Sony Pictures Releasing | true | false |
| 5 | - | Fame | $1,075,033 | - | 276 | - | $3,895 | $1,276,622 | 1 | Filmax | true | false |
| 6 | 2 | Spanish Movie | $973,225 | -9.2% | 334 | -32 | $2,913 | $10,279,201 | 4 | 20th Century Fox International | false | false |
| 7 | 3 | Planet 51 | $943,755 | -10% | 382 | -58 | $2,470 | $15,178,295 | 5 | DeAPlaneta | false | false |
| 8 | 5 | Cell 211 | $909,333 | +56.8% | 213 | -5 | $4,269 | $13,295,430 | 8 | Paramount Pictures International | false | false |
| 9 | - | Ninja Assassin | $626,431 | - | 203 | - | $3,085 | $711,169 | 1 | Warner Bros. | true | false |
| 10 | 4 | Old Dogs | $517,723 | -21.7% | 289 | +65 | $1,791 | $5,249,180 | 4 | Walt Disney Pictures | false | false |
| 11 | 16 | Cloudy with a Chance of Meatballs | $370,274 | +403.2% | 298 | +257 | $1,242 | $5,877,561 | 4 | Sony Pictures Releasing | false | false |
| 12 | - | The Flight Before Christmas | $324,126 | - | 145 | - | $2,235 | $405,420 | 1 | Filmax | true | false |
| 13 | 7 | The Twilight Saga: New Moon | $288,452 | -30% | 195 | -163 | $1,479 | $29,763,356 | 6 | - | false | false |
| 14 | 6 | Where the Wild Things Are | $281,412 | -33.5% | 150 | - | $1,876 | $886,372 | 2 | Warner Bros. | false | false |
| 15 | 10 | The Hedgehog | $279,537 | +12.3% | 89 | -7 | $3,140 | $1,104,097 | 3 | Alta Films | false | false |
| 16 | 8 | 2012 | $268,724 | -23.8% | 171 | -162 | $1,571 | $22,280,842 | 7 | Sony Pictures Releasing | false | false |
| 17 | 9 | What Just Happened | $163,853 | -41.1% | 85 | -65 | $1,927 | $1,261,966 | 3 | Filmax | false | false |
| 18 | 12 | A Christmas Carol | $137,401 | -20.8% | 160 | -65 | $858 | $8,554,299 | 7 | Walt Disney Pictures | false | false |
| 19 | 11 | Armored | $82,883 | -57.7% | 75 | -66 | $1,105 | $970,954 | 3 | Sony Pictures Releasing | false | false |
| 20 | 18 | Agora | $69,041 | +25.5% | 31 | -41 | $2,227 | $31,756,137 | 12 | 20th Century Fox International | false | false |
| 21 | 13 | The Dancer and the Thief | $67,445 | -40.6% | 49 | -70 | $1,376 | $2,241,275 | 5 | Notro Films | false | false |
| 22 | 17 | Blame It on Mum | $62,343 | -12.4% | 27 | -1 | $2,309 | $157,922 | 2 | Golem Distribución | false | false |
| 23 | - | In the Loop | $54,012 | - | 22 | - | $2,455 | $470,838 | 4 | N/A | false | false |
| 24 | 14 | Paranormal Activity | $51,952 | -53.8% | 42 | -112 | $1,236 | $2,860,245 | 5 | Warner Bros. | false | false |
| 25 | - | Garbo: The Spy | $28,906 | - | 6 | - | $4,817 | $152,826 | 4 | N/A | false | false |
| 26 | 15 | Sorority Row | $25,654 | -65.6% | 38 | -102 | $675 | $7,787,224 | 4 | - | false | false |
| 27 | - | Whatever Works | $24,688 | - | 8 | - | $3,086 | $6,138,913 | 13 | TriPictures | false | false |
| 28 | - | Bad Day to Go Fishing | $22,262 | - | 14 | - | $1,590 | $103,110 | 3 | Notro Films | false | false |
