| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | A Christmas Carol | $4,638,059 | - | 493 | - | $9,407 | $5,013,014 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Cado dalle nubi | $3,584,357 | -10.9% | 430 | +6 | $8,335 | $9,713,164 | 2 | Medusa Distribuzione | false | false |
| 3 | 4 | Dorian Gray | $1,711,424 | -15.2% | 238 | +24 | $7,190 | $4,746,105 | 2 | Eagle Pictures | false | false |
| 4 | 2 | The Twilight Saga: New Moon | $998,532 | -72.3% | 378 | -303 | $2,641 | $23,180,771 | 3 | Eagle Pictures | false | false |
| 5 | - | A Serious Man | $940,924 | - | 217 | - | $4,336 | $940,924 | 1 | Medusa Distribuzione | true | false |
| 6 | 3 | 2012 | $782,290 | -64% | 403 | -162 | $1,941 | $19,955,988 | 4 | Sony Pictures Releasing | false | false |
| 7 | - | Couples Retreat | $700,748 | - | 210 | - | $3,336 | $700,748 | 1 | United International Pictures | true | false |
| 8 | - | The Cézanne Affair/The Man Who Will Come | $582,604 | - | 253 | - | $2,302 | $582,604 | 1 | 01 Distribution | true | false |
| 9 | 5 | The Ugly Truth | $566,215 | -42.7% | 205 | - | $2,762 | $1,970,687 | 2 | Sony Pictures Releasing | false | false |
| 10 | 6 | Planet 51 | $322,296 | -63.2% | 181 | -52 | $1,780 | $2,890,908 | 3 | N/A | false | false |
| 11 | 7 | Broken Embraces | $208,157 | -64.2% | 90 | -100 | $2,312 | $4,810,972 | 4 | Warner Bros. | false | false |
| 12 | - | Ninja Assassin | $206,173 | - | 111 | - | $1,857 | $206,173 | 1 | Warner Bros. | true | false |
| 13 | - | Looking for Eric | $202,583 | - | 72 | - | $2,813 | $202,583 | 1 | BIM Distribuzione | true | false |
| 14 | 10 | The Front Line | $106,230 | -63.3% | 52 | -86 | $2,042 | $1,212,724 | 3 | Lucky Red | false | false |
| 15 | 8 | Meno male che ci sei | $98,206 | -81% | 110 | -90 | $892 | $749,395 | 2 | United International Pictures | false | false |
| 16 | 11 | The Men Who Stare at Goats | $65,885 | -74.8% | 37 | -42 | $1,780 | $5,313,797 | 5 | Medusa Distribuzione | false | false |
| 17 | 9 | Public Enemies | $58,404 | -84.7% | - | - | - | $8,206,557 | 5 | United International Pictures | false | false |
| 18 | 13 | 500 Days of Summer | $58,257 | -68.1% | - | - | - | $306,523 | 2 | 20th Century Fox International | false | false |
| 19 | 14 | Tetro | $48,613 | -70.2% | - | - | - | $527,361 | 3 | BIM Distribuzione | false | false |
| 20 | 12 | Up | $26,540 | -88.1% | - | - | - | $23,311,443 | 8 | Walt Disney Pictures | false | false |
| 21 | - | Moon | $21,935 | - | 10 | - | $2,193 | $21,935 | 1 | Sony Pictures Releasing | true | false |
| 22 | 17 | Julie & Julia | $11,186 | -74.9% | 41 | -5 | $272 | $4,385,843 | 7 | Sony Pictures Releasing | false | false |
