| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Twilight Saga: New Moon | $1,329,882 | - | 90 | - | $14,776 | $1,329,882 | 1 | Alfa Films | true | false |
| 2 | 7 | Cloudy with a Chance of Meatballs | $105,758 | +58.4% | 65 | +11 | $1,627 | $1,539,222 | 8 | Sony Pictures Releasing | false | false |
| 3 | - | Two Lovers | $105,740 | - | 19 | - | $5,565 | $105,740 | 1 | Distribution Company | true | false |
| 4 | 2 | The Secret in Their Eyes | $101,324 | -11.4% | 86 | - | $1,178 | $8,944,880 | 15 | Distribution Company | false | false |
| 5 | 1 | Saw VI | $77,859 | -36.3% | 58 | +2 | $1,342 | $506,664 | 3 | Walt Disney Pictures | false | false |
| 6 | 3 | Whiteout | $73,370 | -24.2% | 30 | - | $2,445 | $192,800 | 2 | Warner Bros. | false | false |
| 7 | - | 500 Days of Summer | $56,568 | - | 12 | - | $4,714 | $56,568 | 1 | 20th Century Fox International | true | false |
| 8 | 6 | The Nightmare Before Christmas 2009 3D Release | $54,682 | -18.4% | 22 | +1 | $2,485 | $251,112 | 3 | Walt Disney Pictures | false | false |
| 9 | 4 | Surrogates | $48,932 | -36% | 49 | +1 | $998 | $733,655 | 5 | Walt Disney Pictures | false | false |
| 10 | 8 | Night Runner | $26,302 | -37.9% | 45 | -6 | $584 | $311,784 | 4 | Alfa Films | false | false |
| 11 | 9 | [Rec]² | $23,026 | -31.5% | 26 | -1 | $885 | $268,303 | 4 | CDI Films | false | false |
| 12 | 5 | This Is It | $22,739 | -66.7% | 67 | -12 | $339 | $636,839 | 4 | Sony Pictures Releasing | false | false |
| 13 | 11 | Boogie | $19,554 | -29.1% | 22 | -13 | $888 | $406,610 | 5 | Distribution Company | false | false |
| 14 | 12 | A Matter of Principles | $16,243 | -21.1% | 30 | -4 | $541 | $532,454 | 9 | N/A | false | false |
| 15 | 16 | The Soloist | $15,029 | -11.4% | 16 | - | $939 | $105,198 | 4 | Paramount Pictures International | false | false |
| 16 | 13 | Paris 36 | $13,016 | -28.1% | 12 | - | $1,084 | $68,117 | 3 | Alfa Films | false | false |
| 17 | 10 | The Last Deadly Mission | $12,716 | -57.4% | 15 | - | $847 | $50,128 | 2 | Pachamama Cine | false | false |
| 18 | 18 | The Burning Plain | $10,334 | -37.5% | 13 | - | $794 | $68,111 | 3 | Impacto Cine | false | false |
| 19 | 19 | Lemon Tree | $10,010 | -28.4% | 11 | - | $910 | $95,195 | 4 | Distribution Company | false | false |
| 20 | 15 | The Brothers Bloom | $9,544 | -45.8% | 13 | -4 | $734 | $130,938 | 5 | Alfa Films | false | false |
| 21 | 17 | My Life in Ruins | $8,324 | -50.7% | 15 | -17 | $554 | $389,607 | 7 | Distribution Company | false | false |
| 22 | 26 | The Final Destination | $7,598 | +4.5% | 15 | - | $506 | $1,733,271 | 10 | Distribution Company | false | false |
| 23 | 22 | The Dolphin: Story of a Dreamer | $6,766 | -27.7% | 20 | - | $338 | $140,600 | 7 | 20th Century Fox International | false | false |
| 24 | 14 | Orphan | $5,820 | -67.6% | 19 | -18 | $306 | $597,765 | 9 | Warner Bros. | false | false |
| 25 | 28 | Shorts | $5,658 | -9.5% | 18 | -2 | $314 | $243,475 | 11 | Warner Bros. | false | false |
| 26 | 23 | Inglourious Basterds | $5,570 | -35.5% | 6 | -1 | $928 | $1,218,171 | 12 | Universal Pictures International (UPI) | false | false |
| 27 | 25 | Welcome to the Sticks | $3,921 | -51.7% | 9 | -6 | $435 | $139,242 | 6 | Distribution Company | false | false |
| 28 | 21 | The Widows of Thursdays | $3,799 | -62% | 13 | -13 | $292 | $1,972,271 | 11 | Alfa Films | false | false |
| 29 | 24 | Broken Embraces | $3,799 | -54.8% | 10 | -11 | $379 | $507,103 | 8 | Universal Pictures International (UPI) | false | false |
| 30 | 29 | Moscow, Belgium | $3,606 | -30.9% | 6 | +1 | $601 | $10,177 | 2 | Primer Plano Film Group | false | false |
| 31 | 20 | Three Wishes | $3,423 | -66.2% | 9 | -9 | $380 | $46,018 | 3 | Distribution Company | false | false |
