| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Up | $6,659,543 | - | 652 | - | $10,214 | $7,138,725 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Inglourious Basterds | $1,750,182 | -28.2% | 393 | -65 | $4,453 | $10,358,298 | 3 | United International Pictures | false | false |
| 3 | 2 | Baaria | $1,209,524 | -41.8% | 362 | -110 | $3,341 | $13,841,202 | 4 | Medusa Distribuzione | false | false |
| 4 | 3 | Fame | $616,604 | -44.5% | 271 | -66 | $2,275 | $2,151,760 | 2 | Lucky Red | false | false |
| 5 | - | Halloween II | $590,516 | - | 207 | - | $2,852 | $590,516 | 1 | Sony Pictures Releasing | true | false |
| 6 | - | Lo spazio bianco | $529,304 | - | 157 | - | $3,371 | $539,872 | 1 | 01 Distribution | true | false |
| 7 | - | Orphan | $507,546 | - | 156 | - | $3,253 | $507,546 | 1 | Warner Bros. | true | false |
| 8 | 5 | Whatever Works | $433,080 | -33.6% | 105 | -53 | $4,124 | $6,483,174 | 5 | Medusa Distribuzione | false | false |
| 9 | 9 | My Life in Ruins | $293,182 | -25.7% | 112 | -15 | $2,617 | $897,066 | 2 | N/A | false | false |
| 10 | - | Purple Sea | $264,893 | - | 86 | - | $3,080 | $264,893 | 1 | Medusa Distribuzione | true | false |
| 11 | 6 | Sword of War | $256,782 | -56.6% | - | - | - | $1,114,120 | 2 | 01 Distribution | false | false |
| 12 | 8 | The Double Hour | $238,571 | -50.5% | - | - | - | $978,587 | 2 | Medusa Distribuzione | false | false |
| 13 | - | Funny People | $146,397 | - | - | - | - | $146,397 | 1 | United International Pictures | true | false |
| 14 | 4 | G-Force | $131,459 | -87% | - | - | - | $5,865,106 | 4 | Walt Disney Pictures | false | false |
| 15 | 11 | Taking Woodstock | $122,532 | -46% | - | - | - | $468,893 | 2 | BIM Distribuzione | false | false |
| 16 | 7 | Ice Age: Dawn of the Dinosaurs | $97,052 | -80.2% | - | - | - | $44,138,683 | 8 | 20th Century Fox International | false | false |
| 17 | 10 | District 9 | $95,334 | -69.4% | 51 | -105 | $1,869 | $2,791,761 | 4 | Sony Pictures Releasing | false | false |
| 18 | 13 | The Taking of Pelham 123 | $78,198 | -53.9% | 28 | -42 | $2,792 | $3,570,744 | 5 | Sony Pictures Releasing | false | false |
| 19 | 12 | The Girl Who Played with Fire | $65,831 | -67.7% | - | - | - | $2,068,868 | 4 | BIM Distribuzione | false | false |
| 20 | 18 | Ricky | $42,994 | -39.1% | - | - | - | $145,504 | 2 | Teodora Film | false | false |
