| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Storm | $670,671 | -22.7% | 111 | +1 | $6,042 | $2,876,288 | 3 | Universal Pictures International (UPI) | false | false |
| 2 | - | The Ugly Truth | $390,972 | - | 73 | - | $5,355 | $551,558 | 1 | Sony Pictures Releasing | true | false |
| 3 | 2 | Inglourious Basterds | $343,252 | -26.8% | 80 | - | $4,290 | $5,531,859 | 6 | Universal Pictures International (UPI) | false | false |
| 4 | - | Spangas on Survival | $324,231 | - | 95 | - | $3,412 | $484,457 | 1 | Walt Disney Pictures | true | false |
| 5 | 3 | Lover or Loser | $255,081 | -28.3% | 100 | +1 | $2,550 | $769,199 | 2 | RCV Film Distribution | false | false |
| 6 | 4 | The Final Destination | $145,640 | -39.9% | 50 | -5 | $2,912 | $2,262,670 | 5 | Warner Bros. | false | false |
| 7 | 5 | The Rebound | $116,932 | -48.5% | 62 | - | $1,886 | $591,627 | 2 | Paradiso Entertainment | false | false |
| 8 | 6 | Dance Flick | $96,736 | -39.1% | 26 | - | $3,720 | $336,086 | 2 | Universal Pictures International (UPI) | false | false |
| 9 | 7 | G-Force | $94,240 | -37.4% | 99 | -6 | $951 | $2,983,164 | 10 | Walt Disney Pictures | false | false |
| 10 | 8 | My Sister's Keeper | $83,510 | -31.9% | 38 | - | $2,197 | $1,334,913 | 6 | Warner Bros. | false | false |
| 11 | 9 | Ice Age: Dawn of the Dinosaurs | $76,249 | -34.7% | 99 | -18 | $770 | $12,951,501 | 14 | 20th Century Fox International | false | false |
| 12 | 13 | The Girl with the Dragon Tattoo | $73,812 | +4.9% | 36 | +3 | $2,050 | $1,455,333 | 9 | Benelux Film Distributors | false | false |
| 13 | 10 | The Taking of Pelham 123 | $62,917 | -42.2% | 40 | -18 | $1,572 | $1,687,632 | 7 | Sony Pictures Releasing | false | false |
| 14 | 11 | Harry Potter and the Half-Blood Prince | $57,396 | -43.5% | 59 | -39 | $972 | $16,439,512 | 12 | Warner Bros. | false | false |
| 15 | 12 | Carriers | $55,195 | -36.4% | 30 | - | $1,839 | $211,963 | 2 | Independent Films | false | false |
| 16 | 14 | 500 Days of Summer | $42,811 | -29% | 14 | -1 | $3,057 | $155,839 | 2 | Warner Bros. | false | false |
| 17 | 15 | Lilly the Witch: The Dragon and the Magic Book | $39,545 | -29.3% | 49 | +10 | $807 | $442,655 | 7 | RCV Film Distribution | false | false |
| 18 | 17 | Broken Embraces | $36,405 | +7.4% | 24 | +2 | $1,516 | $432,842 | 6 | Cinéart | false | false |
| 19 | 16 | The Hangover | $24,516 | -51.5% | 17 | -17 | $1,442 | $5,279,285 | 17 | Warner Bros. | false | false |
| 20 | 20 | Princess Lillifee | $18,609 | -24.5% | 16 | -5 | $1,163 | $98,534 | 3 | Benelux Film Distributors | false | false |
