| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Secret in Their Eyes | $464,970 | -18.7% | 89 | - | $5,224 | $6,787,888 | 8 | Distribution Company | false | false |
| 2 | - | Cloudy with a Chance of Meatballs | $318,817 | - | 70 | - | $4,554 | $318,817 | 1 | Sony Pictures Releasing | true | false |
| 3 | 2 | The Final Destination | $171,066 | -43% | 63 | +10 | $2,715 | $1,227,329 | 3 | Distribution Company | false | false |
| 4 | 3 | The Widows of Thursdays | $143,984 | -32% | 76 | +4 | $1,894 | $1,475,190 | 4 | Alfa Films | false | false |
| 5 | - | Broken Embraces | $141,415 | - | 35 | - | $4,040 | $142,062 | 1 | Universal Pictures International (UPI) | true | false |
| 6 | 4 | District 9 | $94,709 | -38.6% | 45 | - | $2,104 | $293,063 | 2 | Sony Pictures Releasing | false | false |
| 7 | 5 | Orphan | $85,569 | -25.7% | 37 | - | $2,312 | $233,963 | 2 | Warner Bros. | false | false |
| 8 | 6 | A Matter of Principles | $67,860 | -26.1% | 35 | +1 | $1,938 | $189,093 | 2 | N/A | false | false |
| 9 | 7 | Inglourious Basterds | $65,149 | -28.9% | 52 | +2 | $1,252 | $957,257 | 5 | Universal Pictures International (UPI) | false | false |
| 10 | - | Jennifer's Body | $52,522 | - | 26 | - | $2,020 | $52,980 | 1 | 20th Century Fox International | true | false |
| 11 | 8 | Julie & Julia | $46,870 | -46.1% | 35 | -5 | $1,339 | $336,750 | 3 | Sony Pictures Releasing | false | false |
| 12 | 12 | The Ugly Truth | $27,651 | -23.3% | 27 | -4 | $1,024 | $462,078 | 6 | Sony Pictures Releasing | false | false |
| 13 | 11 | Dad for a Day | $24,650 | -44.4% | 57 | -7 | $432 | $1,689,406 | 9 | Walt Disney Pictures | false | false |
| 14 | 9 | The Time Traveler's Wife | $22,223 | -56.7% | 30 | - | $740 | $86,507 | 2 | Distribution Company | false | false |
| 15 | 10 | Tinker Bell and the Lost Treasure | $21,718 | -54.1% | 47 | - | $462 | $483,656 | 5 | Walt Disney Pictures | false | false |
| 16 | 13 | Shorts | $12,471 | -62% | 20 | - | $623 | $165,383 | 4 | Warner Bros. | false | false |
| 17 | 16 | Anita | $10,924 | -32.9% | 41 | -5 | $266 | $383,864 | 6 | Distribution Company | false | false |
| 18 | 15 | The Hangover | $9,718 | -51.3% | 27 | -9 | $359 | $837,746 | 8 | Warner Bros. | false | false |
| 19 | 14 | G-Force | $9,368 | -68.3% | 33 | -8 | $283 | $2,095,310 | 10 | Walt Disney Pictures | false | false |
| 20 | 19 | Cherry Blossoms | $6,930 | -35.1% | 5 | +1 | $1,386 | $37,544 | 3 | Alfa Films | false | false |
| 21 | 17 | Aliens in the Attic | $6,370 | -60.7% | 31 | -1 | $205 | $183,916 | 7 | 20th Century Fox International | false | false |
| 22 | 22 | My Bloody Valentine | $5,224 | -28.6% | 16 | -10 | $326 | $571,567 | 5 | Alfa Films | false | false |
| 23 | 20 | My Best Friend's Girl | $4,578 | -46.2% | 7 | -5 | $654 | $65,444 | 3 | Alfa Films | false | false |
| 24 | 21 | The Haunting in Connecticut | $4,533 | -44.8% | 11 | -4 | $412 | $190,945 | 7 | Alfa Films | false | false |
| 25 | 24 | The Wave | $3,703 | -34.1% | 5 | - | $740 | $177,739 | 7 | Impacto Cine | false | false |
| 26 | 18 | Ice Age: Dawn of the Dinosaurs | $3,463 | -77.8% | 12 | -8 | $288 | $8,066,225 | 14 | 20th Century Fox International | false | false |
| 27 | 27 | Traitor | $2,876 | -30.1% | 8 | -2 | $359 | $60,262 | 4 | Distribution Company | false | false |
| 28 | 23 | Coco Before Chanel | $2,691 | -54.2% | 10 | -1 | $269 | $205,437 | 6 | Warner Bros. | false | false |
| 29 | - | Street Fighter: The Legend of Chun-Li | $2,623 | - | 5 | - | $524 | $2,623 | 1 | Distribution Company | true | false |
| 30 | 26 | Homero Manzi, un poeta en la tormenta | $2,389 | -45.8% | 5 | - | $477 | $9,807 | 2 | Primer Plano Film Group | false | false |
| 31 | 31 | Hannah Montana: The Movie | $2,296 | +28% | 7 | -6 | $328 | $455,797 | 8 | Walt Disney Pictures | false | false |
| 32 | 25 | Giovanna's Father 2009 Re-release | $1,675 | -64.3% | 4 | -1 | $418 | $7,941 | 2 | Primer Plano Film Group | false | false |
| 33 | 28 | Drag Me to Hell | $626 | -75.6% | 5 | -7 | $125 | $448,351 | 8 | Universal Pictures International (UPI) | false | false |
| 34 | 47 | G.I. Joe: The Rise of Cobra | $600 | +605.9% | 4 | +3 | $150 | $451,361 | 9 | Paramount Pictures International | false | false |
| 35 | 35 | Tierra sublevada: Oro impuro | $533 | -23.9% | 1 | -1 | $533 | $12,647 | 4 | Primer Plano Film Group | false | false |
| 36 | 34 | The Secret of the Grain | $469 | -39.6% | 2 | - | $234 | $82,776 | 10 | N/A | false | false |
| 37 | 37 | El hombre que corría tras el viento | $437 | +27.4% | 2 | -2 | $218 | $35,527 | 5 | Primer Plano Film Group | false | false |
| 38 | 50 | Defiance | $234 | +654.8% | 2 | +1 | $117 | $120,048 | 9 | N/A | false | false |
| 39 | 40 | Mentiras piadosas | $200 | -27.5% | 2 | +1 | $100 | $19,290 | 7 | N/A | false | false |
| 40 | 38 | The Dress | $154 | -51.3% | 4 | +1 | $38 | $5,832 | 3 | Primer Plano Film Group | false | false |
| 41 | 32 | Wild Blood | $141 | -90.5% | 1 | -3 | $141 | $21,052 | 5 | Pachamama Cine | false | false |
| 42 | 29 | Harry Potter and the Half-Blood Prince | $96 | -95.8% | 1 | -2 | $96 | $4,461,478 | 11 | Warner Bros. | false | false |
| 43 | 46 | Breath 2009 Re-release | $73 | -17% | 1 | - | $73 | $20,461 | 10 | Distribution Company | false | false |
| 44 | 45 | A Christmas Tale | $62 | -45.6% | 1 | - | $62 | $90,076 | 14 | Pachamama Cine | false | false |
| 45 | 39 | Transformers: Revenge of the Fallen | $61 | -78.3% | 1 | -1 | $61 | $2,490,832 | 15 | Paramount Pictures International | false | false |
| 46 | 48 | Inspector Bellamy | $52 | -23.5% | 1 | - | $52 | $140,116 | 18 | Alfa Films | false | false |
| 47 | 49 | The Reader | $42 | -26.3% | 1 | - | $42 | $570,036 | 22 | Pachamama Cine | false | false |
| 48 | 30 | The Age of Stupid | $33 | -98.5% | 1 | -1 | $33 | $2,224 | 2 | N/A | false | false |
