| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Cloudy with a Chance of Meatballs | $99,016 | -22.8% | 38 | - | $2,605 | $258,390 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Shorts | $54,991 | - | 23 | - | $2,390 | $54,991 | 1 | Importadora El Rosado | true | false |
| 3 | 2 | The Ugly Truth | $37,840 | -24% | 22 | - | $1,720 | $210,960 | 3 | Sony Pictures Releasing | false | false |
| 4 | - | Year One | $30,666 | - | 14 | - | $2,190 | $30,666 | 1 | Sony Pictures Releasing | true | false |
| 5 | 4 | The Last House on the Left | $28,405 | -16.3% | 15 | - | $1,893 | $78,053 | 2 | United International Pictures | false | false |
| 6 | 3 | Aliens in the Attic | $21,875 | -44.5% | 23 | +1 | $951 | $162,317 | 3 | 20th Century Fox International | false | false |
| 7 | 5 | Tinker Bell and the Lost Treasure | $8,845 | -44% | 15 | - | $589 | $141,310 | 4 | Walt Disney Pictures | false | false |
| 8 | 6 | My Bloody Valentine | $8,153 | -20.5% | 15 | +7 | $543 | $419,582 | 5 | N/A | false | false |
| 9 | 9 | G-Force | $2,709 | -48.9% | 16 | -7 | $169 | $1,458,830 | 9 | Walt Disney Pictures | false | false |
| 10 | 10 | The Hangover | $2,301 | -38.2% | 5 | -3 | $460 | $187,109 | 6 | Importadora El Rosado | false | false |
| 11 | 7 | The Taking of Pelham 123 | $2,214 | -67.1% | 5 | -10 | $442 | $161,629 | 5 | Sony Pictures Releasing | false | false |
| 12 | 19 | Public Enemies | $1,807 | +523.1% | 6 | +2 | $301 | $77,495 | 6 | United International Pictures | false | false |
| 13 | 11 | The Accidental Husband | $1,459 | -58.1% | 15 | +3 | $97 | $173,532 | 6 | Walt Disney Pictures | false | false |
| 14 | 12 | State of Play | $1,308 | -62% | 6 | -6 | $218 | $47,337 | 4 | United International Pictures | false | false |
| 15 | 13 | G.I. Joe: The Rise of Cobra | $1,256 | -48.2% | 5 | -2 | $251 | $619,555 | 8 | United International Pictures | false | false |
| 16 | 15 | The Proposal | $1,066 | -17% | 2 | - | $533 | $310,883 | 12 | Walt Disney Pictures | false | false |
| 17 | 14 | The Unborn | $668 | -57.2% | 5 | -1 | $133 | $209,544 | 7 | United International Pictures | false | false |
| 18 | 17 | Ice Age: Dawn of the Dinosaurs | $298 | -27% | 11 | +4 | $27 | $2,451,425 | 13 | 20th Century Fox International | false | false |
| 19 | 18 | 12 Rounds | $78 | -75.1% | 1 | -1 | $78 | $34,487 | 7 | 20th Century Fox International | false | false |
