| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Secret in Their Eyes | $571,666 | +10.3% | 89 | +10 | $6,423 | $6,095,727 | 7 | Distribution Company | false | false |
| 2 | 2 | The Final Destination | $300,376 | -37.3% | 53 | -16 | $5,667 | $977,228 | 2 | Distribution Company | false | false |
| 3 | 3 | The Widows of Thursdays | $211,884 | -37.6% | 72 | +3 | $2,942 | $1,269,944 | 3 | Alfa Films | false | false |
| 4 | - | District 9 | $154,348 | - | 45 | - | $3,429 | $154,348 | 1 | Sony Pictures Releasing | true | false |
| 5 | - | Orphan | $115,184 | - | 37 | - | $3,113 | $115,184 | 1 | Warner Bros. | true | false |
| 6 | - | A Matter of Principles | $91,855 | - | 34 | - | $2,701 | $91,855 | 1 | N/A | true | false |
| 7 | 5 | Inglourious Basterds | $91,675 | -31.2% | 50 | +3 | $1,833 | $860,467 | 4 | Universal Pictures International (UPI) | false | false |
| 8 | 4 | Julie & Julia | $86,952 | -39.5% | 40 | - | $2,173 | $270,458 | 2 | Sony Pictures Releasing | false | false |
| 9 | - | The Time Traveler's Wife | $51,341 | - | 30 | - | $1,711 | $51,341 | 1 | Distribution Company | true | false |
| 10 | 7 | Tinker Bell and the Lost Treasure | $47,331 | -27.4% | 47 | - | $1,007 | $446,712 | 4 | Walt Disney Pictures | false | false |
| 11 | 6 | Dad for a Day | $44,319 | -33.3% | 64 | -7 | $692 | $1,646,604 | 8 | Walt Disney Pictures | false | false |
| 12 | 8 | The Ugly Truth | $36,052 | -24.8% | 31 | - | $1,162 | $423,938 | 5 | Sony Pictures Releasing | false | false |
| 13 | 9 | Shorts | $32,840 | -18.8% | 20 | - | $1,642 | $145,943 | 3 | Warner Bros. | false | false |
| 14 | 10 | G-Force | $29,523 | -23.4% | 41 | -10 | $720 | $2,075,274 | 9 | Walt Disney Pictures | false | false |
| 15 | 12 | The Hangover | $19,946 | -42.8% | 36 | -6 | $554 | $821,482 | 7 | Warner Bros. | false | false |
| 16 | 13 | Anita | $16,277 | -29.6% | 46 | -1 | $353 | $362,644 | 5 | Distribution Company | false | false |
| 17 | 16 | Aliens in the Attic | $16,218 | -9.7% | 32 | - | $506 | $173,072 | 6 | 20th Century Fox International | false | false |
| 18 | 14 | Ice Age: Dawn of the Dinosaurs | $15,624 | -27.3% | 20 | -9 | $781 | $8,047,316 | 13 | 20th Century Fox International | false | false |
| 19 | 20 | Cherry Blossoms | $10,677 | +5.6% | 4 | - | $2,669 | $27,076 | 2 | Alfa Films | false | false |
| 20 | 11 | My Best Friend's Girl | $8,508 | -77% | 12 | -13 | $709 | $58,674 | 2 | Alfa Films | false | false |
| 21 | 18 | The Haunting in Connecticut | $8,218 | -33.2% | 15 | -9 | $547 | $183,850 | 6 | Alfa Films | false | false |
| 22 | 15 | My Bloody Valentine | $7,317 | -65% | 26 | -15 | $281 | $563,364 | 4 | Alfa Films | false | false |
| 23 | 17 | Coco Before Chanel | $5,880 | -62% | 11 | -6 | $534 | $199,843 | 5 | Warner Bros. | false | false |
| 24 | 21 | The Wave | $5,615 | -42% | 5 | -6 | $1,123 | $171,676 | 6 | Impacto Cine | false | false |
| 25 | - | Giovanna's Father 2009 Re-release | $4,697 | - | 5 | - | $939 | $4,697 | 1 | Primer Plano Film Group | true | false |
| 26 | - | Homero Manzi, un poeta en la tormenta | $4,410 | - | 5 | - | $882 | $4,410 | 1 | Primer Plano Film Group | true | false |
| 27 | 23 | Traitor | $4,117 | -52.6% | 10 | -9 | $411 | $55,789 | 3 | Distribution Company | false | false |
| 28 | 19 | Drag Me to Hell | $2,564 | -78.1% | 12 | -20 | $213 | $446,190 | 7 | Universal Pictures International (UPI) | false | false |
| 29 | 24 | Harry Potter and the Half-Blood Prince | $2,301 | -57.8% | 3 | -3 | $767 | $4,452,836 | 10 | Warner Bros. | false | false |
| 30 | - | The Age of Stupid | $2,187 | - | 2 | - | $1,093 | $2,187 | 1 | N/A | true | false |
| 31 | 22 | Hannah Montana: The Movie | $1,794 | -79.8% | 13 | -34 | $138 | $452,029 | 7 | Walt Disney Pictures | false | false |
| 32 | 39 | Wild Blood | $1,487 | +321.2% | 4 | +2 | $371 | $20,286 | 4 | Pachamama Cine | false | false |
| 33 | 27 | My Sister's Keeper | $1,009 | -55% | 6 | -8 | $168 | $190,710 | 8 | Distribution Company | false | false |
| 34 | 30 | The Secret of the Grain | $776 | -43.5% | 2 | -3 | $388 | $81,968 | 9 | N/A | false | false |
| 35 | 29 | Tierra sublevada: Oro impuro | $700 | -52.5% | 2 | -1 | $350 | $11,486 | 3 | Primer Plano Film Group | false | false |
| 36 | 34 | Last Chance Harvey | $357 | -58.2% | 2 | -1 | $178 | $472,455 | 17 | Distribution Company | false | false |
| 37 | 48 | El hombre que corría tras el viento | $343 | +535.2% | 4 | +2 | $85 | $34,861 | 4 | Primer Plano Film Group | false | false |
| 38 | 26 | The Dress | $316 | -89.8% | 3 | -2 | $105 | $5,093 | 2 | Primer Plano Film Group | false | false |
| 39 | 51 | Transformers: Revenge of the Fallen | $281 | +1,461.1% | 2 | +1 | $140 | $2,486,000 | 14 | Paramount Pictures International | false | false |
| 40 | 40 | Mentiras piadosas | $276 | +50.8% | 1 | - | $276 | $19,017 | 6 | N/A | false | false |
| 41 | 52 | Pride and Glory | $200 | +4,900% | 1 | - | $200 | $133,700 | 14 | Distribution Company | false | false |
| 42 | 31 | The Taking of Pelham 123 | $168 | -87.7% | 2 | -8 | $84 | $972,372 | 11 | Sony Pictures Releasing | false | false |
| 43 | 50 | The Proposal | $147 | +250% | 3 | +2 | $49 | $885,702 | 13 | Walt Disney Pictures | false | false |
| 44 | 25 | Public Enemies | $127 | -97.5% | 1 | -11 | $127 | $1,018,037 | 9 | Universal Pictures International (UPI) | false | false |
| 45 | 47 | A Christmas Tale | $114 | +83.9% | 1 | - | $114 | $89,823 | 13 | Pachamama Cine | false | false |
| 46 | 41 | Breath 2009 Re-release | $88 | -11.1% | 1 | - | $88 | $20,321 | 9 | Distribution Company | false | false |
| 47 | 44 | G.I. Joe: The Rise of Cobra | $85 | -4.5% | 1 | -1 | $85 | $449,885 | 8 | Paramount Pictures International | false | false |
| 48 | 42 | Inspector Bellamy | $68 | -31.3% | 1 | - | $68 | $139,762 | 17 | Alfa Films | false | false |
| 49 | 49 | The Reader | $57 | +9.6% | 1 | - | $57 | $568,876 | 21 | Pachamama Cine | false | false |
| 50 | 43 | Defiance | $31 | -66.3% | 1 | - | $31 | $119,584 | 8 | N/A | false | false |
| 51 | 32 | The Girl by the Lake 2009 Re-release | $27 | -97.6% | 1 | -2 | $27 | $23,006 | 5 | Primer Plano Film Group | false | false |
| 52 | 45 | Days and Clouds | $21 | -72% | 1 | - | $21 | $96,433 | 10 | Impacto Cine | false | false |
