| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Storm | $635,318 | - | 111 | - | $5,723 | $640,633 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Inglourious Basterds | $478,898 | -25.5% | 80 | -1 | $5,986 | $4,389,891 | 4 | Universal Pictures International (UPI) | false | false |
| 3 | 2 | The Final Destination | $293,504 | -33.6% | 56 | -3 | $5,241 | $1,725,200 | 3 | Warner Bros. | false | false |
| 4 | 4 | My Sister's Keeper | $147,496 | -4% | 39 | +1 | $3,781 | $1,008,084 | 4 | Warner Bros. | false | false |
| 5 | 3 | Harry Potter and the Half-Blood Prince | $139,652 | -18.2% | 134 | -19 | $1,042 | $16,395,976 | 10 | Warner Bros. | false | false |
| 6 | 5 | G-Force | $124,824 | -4.1% | 105 | +2 | $1,188 | $2,652,288 | 8 | Walt Disney Pictures | false | false |
| 7 | 6 | The Taking of Pelham 123 | $114,703 | -10.7% | 68 | -2 | $1,686 | $1,455,288 | 5 | Sony Pictures Releasing | false | false |
| 8 | 7 | Ice Age: Dawn of the Dinosaurs | $102,375 | -14% | 124 | -1 | $825 | $12,805,294 | 12 | 20th Century Fox International | false | false |
| 9 | 8 | The Girl with the Dragon Tattoo | $73,483 | -13.6% | 37 | -4 | $1,986 | $1,250,885 | 7 | Benelux Film Distributors | false | false |
| 10 | 10 | The Hangover | $60,433 | -9% | 48 | -2 | $1,259 | $5,220,244 | 15 | Warner Bros. | false | false |
| 11 | 9 | Funny People | $57,704 | -27.3% | 30 | - | $1,923 | $338,421 | 3 | Universal Pictures International (UPI) | false | false |
| 12 | 12 | The Proposal | $47,737 | -9.7% | 53 | -1 | $900 | $4,391,812 | 14 | Walt Disney Pictures | false | false |
| 13 | 15 | Broken Embraces | $38,426 | -19.1% | 21 | -2 | $1,829 | $332,164 | 4 | Cinéart | false | false |
| 14 | 16 | Lilly the Witch: The Dragon and the Magic Book | $37,028 | -6% | 50 | - | $740 | $308,407 | 5 | RCV Film Distribution | false | false |
| 15 | - | Princess Lillifee | $27,703 | - | 21 | - | $1,319 | $34,348 | 1 | Benelux Film Distributors | true | false |
