| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Up | $364,737 | -43.8% | 86 | -5 | $4,241 | $1,105,353 | 2 | Walt Disney Pictures | false | false |
| 2 | - | G.I. Joe: The Rise of Cobra | $324,504 | - | 53 | - | $6,122 | $324,504 | 1 | United International Pictures | true | false |
| 3 | 2 | The Final Destination | $253,633 | -40.2% | 28 | -6 | $9,058 | $823,716 | 2 | Roadshow Films | false | false |
| 4 | - | Love Happens | $141,692 | - | 30 | - | $4,723 | $141,692 | 1 | Odeon | true | false |
| 5 | 4 | Inglourious Basterds | $94,117 | -42.8% | 55 | -2 | $1,711 | $2,063,887 | 5 | United International Pictures | false | false |
| 6 | - | Bad Lieutenant: Port of Call New Orleans | $89,362 | - | 23 | - | $3,885 | $89,362 | 1 | Odeon | true | false |
| 7 | 3 | Harry Potter and the Half-Blood Prince | $68,338 | -65.8% | 49 | -45 | $1,394 | $3,296,589 | 4 | Warner Bros. | false | false |
| 8 | 8 | Ice Age: Dawn of the Dinosaurs | $50,942 | +1.4% | 40 | -3 | $1,273 | $4,660,369 | 12 | 20th Century Fox International | false | false |
| 9 | 5 | Gamer | $47,356 | -66.2% | 30 | -5 | $1,578 | $659,879 | 3 | Odeon | false | false |
| 10 | 6 | Drag Me to Hell | $35,925 | -50.8% | 15 | -2 | $2,395 | $140,867 | 2 | Spentzos Films | false | false |
