| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Up | $284,433 | - | 73 | - | $3,896 | $284,433 | 1 | Ster-Kinekor Pictures | true | false |
| 2 | 1 | District 9 | $122,365 | -33.8% | 79 | -2 | $1,548 | $830,751 | 3 | Ster-Kinekor Pictures | false | false |
| 3 | - | The Time Traveler's Wife | $93,758 | - | 40 | - | $2,343 | $93,758 | 1 | NuMetro Distribution | true | false |
| 4 | 2 | Public Enemies | $61,618 | -37.3% | 63 | - | $978 | $218,174 | 2 | United International Pictures | false | false |
| 5 | 3 | G.I. Joe: The Rise of Cobra | $61,017 | -31.7% | 73 | - | $835 | $1,015,946 | 5 | United International Pictures | false | false |
| 6 | 5 | The Proposal | $54,856 | -19.4% | 59 | -3 | $929 | $2,474,831 | 10 | Ster-Kinekor Pictures | false | false |
| 7 | 6 | My Sister's Keeper | $44,812 | -25.8% | 46 | - | $974 | $641,341 | 5 | NuMetro Distribution | false | false |
| 8 | 4 | G-Force | $37,679 | -53% | 50 | -12 | $753 | $1,124,872 | 7 | Ster-Kinekor Pictures | false | false |
| 9 | - | Crank: High Voltage | $28,386 | - | 25 | - | $1,135 | $28,386 | 1 | Ster-Kinekor Pictures | true | false |
| 10 | 8 | Coco Before Chanel | $17,147 | -15.3% | 9 | - | $1,905 | $96,697 | 3 | NuMetro Distribution | false | false |
| 11 | 7 | Year One | $16,930 | -34.6% | 17 | -2 | $995 | $161,913 | 4 | Ster-Kinekor Pictures | false | false |
| 12 | - | Dance Flick | $12,482 | - | 10 | - | $1,248 | $12,482 | 1 | United International Pictures | true | false |
| 13 | 13 | Not Easily Broken | $10,183 | -24.3% | 18 | -1 | $565 | $97,566 | 4 | NuMetro Distribution | false | false |
| 14 | 9 | The Hangover | $10,150 | -48% | 17 | -16 | $597 | $1,984,545 | 13 | NuMetro Distribution | false | false |
| 15 | 10 | Fired Up! | $10,129 | -46.1% | 18 | -8 | $562 | $286,235 | 6 | Ster-Kinekor Pictures | false | false |
| 16 | 11 | My Life in Ruins | $9,325 | -49.7% | 18 | -10 | $518 | $376,058 | 7 | Ster-Kinekor Pictures | false | false |
| 17 | 16 | Adam | $6,335 | -29.8% | 9 | - | $703 | $21,101 | 2 | NuMetro Distribution | false | false |
| 18 | 14 | Orphan | $5,161 | -58.4% | 16 | -3 | $322 | $94,675 | 4 | NuMetro Distribution | false | false |
| 19 | 12 | Ice Age: Dawn of the Dinosaurs | $4,744 | -71.7% | 13 | -19 | $364 | $3,492,517 | 11 | NuMetro Distribution | false | false |
| 20 | 18 | Disgrace | $3,722 | -21% | 8 | -1 | $465 | $58,962 | 5 | United International Pictures | false | false |
| 21 | 19 | A Summer in Genoa | $2,528 | -35.3% | 5 | -3 | $505 | $62,544 | 6 | United International Pictures | false | false |
| 22 | 17 | Fighting | $2,519 | -53.3% | 11 | -9 | $229 | $258,263 | 8 | United International Pictures | false | false |
| 23 | 23 | Knowing | $477 | -79.1% | 4 | -2 | $119 | $877,218 | 11 | United International Pictures | false | false |
| 24 | - | Heaven on Earth | $228 | - | 1 | - | $228 | $18,472 | 7 | Ster-Kinekor Pictures | false | false |
