| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | District 9 | $1,972,507 | -47.4% | 446 | -1 | $4,422 | $7,966,575 | 2 | Sony Pictures Releasing | false | false |
| 2 | 2 | The Final Destination | $1,547,683 | -52.5% | 385 | -42 | $4,019 | $17,789,953 | 3 | Entertainment Film Distributors | false | false |
| 3 | - | Dorian Gray | $1,470,810 | - | 348 | - | $4,226 | $1,470,810 | 1 | Momentum Pictures | true | false |
| 4 | - | Sorority Row | $1,303,511 | - | 345 | - | $3,778 | $1,303,511 | 1 | Entertainment One | true | false |
| 5 | 3 | 500 Days of Summer | $970,069 | -52.4% | 317 | +1 | $3,060 | $4,012,089 | 2 | 20th Century Fox International | false | false |
| 6 | - | Julie & Julia | $900,060 | - | 359 | - | $2,507 | $900,060 | 1 | Sony Pictures Releasing | true | false |
| 7 | 4 | Inglourious Basterds | $619,176 | -50.6% | 343 | -102 | $1,805 | $15,783,248 | 4 | Universal Pictures International (UPI) | false | false |
| 8 | 6 | Aliens in the Attic | $441,905 | -45.9% | 441 | -8 | $1,002 | $10,047,716 | 6 | 20th Century Fox International | false | false |
| 9 | 5 | Funny People | $364,790 | -62% | 318 | -63 | $1,147 | $5,289,446 | 3 | Universal Pictures International (UPI) | false | false |
| 10 | - | Adventureland | $350,855 | - | 204 | - | $1,719 | $350,855 | 1 | Walt Disney Pictures | true | false |
| 11 | 8 | G-Force | $338,927 | -40.9% | 357 | -26 | $949 | $22,011,541 | 7 | Walt Disney Pictures | false | false |
| 12 | 7 | The Time Traveler's Wife | $285,907 | -60.8% | 286 | -106 | $999 | $12,171,979 | 5 | Entertainment Film Distributors | false | false |
| 13 | - | Whiteout | $251,470 | - | 264 | - | $952 | $251,470 | 1 | Optimum Releasing | true | false |
| 14 | 9 | Harry Potter and the Half-Blood Prince | $187,529 | -64.9% | 265 | -58 | $707 | $84,089,250 | 9 | Warner Bros. | false | false |
| 15 | - | Fish Tank | $171,838 | - | 47 | - | $3,656 | $171,838 | 1 | Artificial Eye | true | false |
