| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Inglourious Basterds | $18,053 | -11.5% | 6 | - | $3,008 | $106,484 | 3 | United International Pictures | false | false |
| 2 | 2 | Ice Age: Dawn of the Dinosaurs | $9,734 | +0.5% | 9 | - | $1,081 | $359,725 | 10 | 20th Century Fox International | false | false |
| 3 | 3 | The Taking of Pelham 123 | $6,331 | -3.1% | 5 | - | $1,266 | $20,786 | 2 | Sony Pictures Releasing | false | false |
| 4 | 7 | Two Lovers | $5,117 | +97.3% | 3 | - | $1,705 | $8,314 | 2 | N/A | false | false |
| 5 | 4 | The Proposal | $4,719 | -18.1% | 6 | - | $786 | $98,370 | 7 | Walt Disney Pictures | false | false |
| 6 | 5 | G-Force | $4,685 | -8.3% | 5 | - | $937 | $17,514 | 2 | Walt Disney Pictures | false | false |
| 7 | 6 | Harry Potter and the Half-Blood Prince | $2,687 | -43.6% | 8 | - | $335 | $182,326 | 8 | Warner Bros. | false | false |
| 8 | 9 | Public Enemies | $2,268 | +15.4% | 5 | - | $453 | $72,561 | 10 | United International Pictures | false | false |
| 9 | 8 | The Hangover | $1,572 | -21.2% | 5 | - | $314 | $139,183 | 12 | Warner Bros. | false | false |
| 10 | 10 | Knowing | $1,043 | -29.9% | 4 | - | $260 | $25,196 | 6 | N/A | false | false |
| 11 | 11 | Brüno | $850 | -28% | 5 | -1 | $170 | $63,898 | 9 | N/A | false | false |
| 12 | 12 | State of Play | $697 | -17.1% | 4 | - | $174 | $30,717 | 13 | United International Pictures | false | false |
| 13 | 13 | Coraline | $508 | -1.9% | 4 | - | $127 | $33,599 | 14 | United International Pictures | false | false |
| 14 | 14 | Transformers: Revenge of the Fallen | $325 | -9.7% | 8 | - | $40 | $81,971 | 11 | United International Pictures | false | false |
| 15 | 15 | Hannah Montana: The Movie | $249 | -16.4% | 5 | - | $49 | $32,099 | 13 | Walt Disney Pictures | false | false |
| 16 | - | Hotel for Dogs | $234 | - | 6 | - | $39 | $33,552 | 20 | United International Pictures | false | false |
| 17 | 18 | Ghosts of Girlfriends Past | $229 | +30.1% | 5 | - | $45 | $58,612 | 13 | Warner Bros. | false | false |
| 18 | 17 | Terminator Salvation | $221 | -1.8% | 4 | - | $55 | $91,571 | 14 | Sony Pictures Releasing | false | false |
| 19 | 20 | Night at the Museum: Battle of the Smithsonian | $115 | +36.9% | 6 | - | $19 | $60,700 | 16 | 20th Century Fox International | false | false |
| 20 | 16 | Angels & Demons | $108 | -62.8% | 1 | -3 | $108 | $164,327 | 17 | Sony Pictures Releasing | false | false |
| 21 | - | Taken | $23 | - | 2 | - | $11 | $4,982 | 12 | N/A | false | false |
