| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | My Bloody Valentine | $24,367 | - | 7 | - | $3,481 | $39,143 | 1 | N/A | true | false |
| 2 | 1 | The Hangover | $19,920 | +30.8% | 6 | - | $3,320 | $112,666 | 4 | Warner Bros. | false | false |
| 3 | 2 | G-Force | $14,614 | +24.4% | 9 | - | $1,623 | $105,702 | 4 | Walt Disney Pictures | false | false |
| 4 | 3 | Bad Day to Go Fishing | $10,806 | +6% | 5 | - | $2,161 | $44,180 | 3 | N/A | false | false |
| 5 | - | The Accidental Husband | $8,883 | - | 5 | - | $1,776 | $8,883 | 1 | Walt Disney Pictures | true | false |
| 6 | 4 | The Proposal | $8,831 | +27.8% | 4 | -2 | $2,207 | $142,515 | 7 | Walt Disney Pictures | false | false |
| 7 | 5 | Public Enemies | $7,672 | +30.9% | 6 | -1 | $1,278 | $33,485 | 3 | Universal Pictures International (UPI) | false | false |
| 8 | 7 | Harry Potter and the Half-Blood Prince | $3,625 | +27.3% | 3 | -3 | $1,208 | $291,360 | 8 | Warner Bros. | false | false |
| 9 | 6 | Pride and Glory | $3,560 | -18.6% | 4 | - | $890 | $9,679 | 2 | N/A | false | false |
| 10 | 8 | Ice Age: Dawn of the Dinosaurs | $2,774 | +25.5% | 5 | -1 | $554 | $915,091 | 10 | 20th Century Fox International | false | false |
| 11 | 14 | Shorts | $2,230 | +147% | 4 | - | $557 | $17,070 | 5 | Warner Bros. | false | false |
| 12 | 10 | Ghosts of Girlfriends Past | $2,157 | +10.4% | 2 | -1 | $1,078 | $38,090 | 5 | N/A | false | false |
| 13 | 11 | The Secrets | $1,942 | +4.9% | 1 | - | $1,942 | $4,527 | 2 | N/A | false | false |
| 14 | - | La Receta | $1,692 | - | 3 | - | $564 | $1,692 | 1 | N/A | true | false |
| 15 | - | Cloud 9 | $1,478 | - | 1 | - | $1,478 | $2,950 | 2 | N/A | false | false |
| 16 | - | Rumba | $1,295 | - | 2 | - | $647 | $1,295 | 1 | N/A | true | false |
| 17 | 9 | The Class | $1,157 | -41.6% | 2 | -1 | $578 | $26,892 | 6 | N/A | false | false |
| 18 | 15 | The Edge of Heaven | $670 | -12.1% | 1 | -1 | $670 | $26,846 | 8 | N/A | false | false |
| 19 | 12 | The Reader | $505 | -63% | 1 | -2 | $505 | $92,274 | 11 | N/A | false | false |
| 20 | 16 | The Zone | $409 | -27.7% | 1 | -1 | $409 | $6,921 | 4 | N/A | false | false |
| 21 | 19 | Hannah Montana: The Movie | $183 | -23.1% | 1 | - | $183 | $57,425 | 12 | Walt Disney Pictures | false | false |
| 22 | 13 | Inspector Bellamy | $155 | -85% | 1 | -1 | $155 | $10,467 | 4 | N/A | false | false |
