| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Inglourious Basterds | $2,028,096 | -27.8% | 508 | - | $3,992 | $19,434,106 | 4 | Universal Pictures International (UPI) | false | false |
| 2 | - | Le coach | $1,810,639 | - | 345 | - | $5,248 | $1,810,639 | 1 | Mars Distribution | true | false |
| 3 | 2 | Neuilly Yo Mama! | $1,680,782 | -11.2% | 469 | +25 | $3,583 | $15,386,966 | 5 | TFM Distribution | false | false |
| 4 | 5 | A Prophet | $1,282,872 | -20.2% | 355 | +33 | $3,613 | $6,231,350 | 3 | UGC Distribution | false | false |
| 5 | - | Gamer | $1,278,377 | - | 342 | - | $3,737 | $1,278,377 | 1 | N/A | true | false |
| 6 | 4 | Up | $1,255,826 | -23.3% | 624 | -35 | $2,012 | $34,620,142 | 7 | Walt Disney Pictures | false | false |
| 7 | 3 | The Final Destination | $1,137,021 | -32.2% | 399 | +7 | $2,849 | $7,623,645 | 3 | Metropolitan Filmexport | false | false |
| 8 | 7 | Making Plans for Lena | $801,460 | -25.6% | 230 | +30 | $3,484 | $2,143,783 | 2 | N/A | false | false |
| 9 | 6 | The Ugly Truth | $778,572 | -27.7% | 252 | -6 | $3,089 | $4,413,861 | 3 | Sony Pictures Releasing | false | false |
| 10 | 8 | Regrets | $417,564 | -36.2% | 146 | +16 | $2,860 | $1,214,286 | 2 | Mars Distribution | false | false |
| 11 | 9 | Ice Age: Dawn of the Dinosaurs | $373,439 | -30.8% | 359 | -62 | $1,040 | $68,160,270 | 11 | 20th Century Fox International | false | false |
| 12 | - | My Sister's Keeper | $369,681 | - | 135 | - | $2,738 | $369,681 | 1 | Metropolitan Filmexport | true | false |
| 13 | 13 | The Hangover | $360,128 | -1.4% | 188 | -2 | $1,915 | $16,665,085 | 12 | Warner Bros. | false | false |
| 14 | 10 | 9 | $337,640 | -36.9% | 342 | -72 | $987 | $4,176,839 | 4 | SND Films | false | false |
| 15 | 12 | Partir | $255,718 | -36.3% | 305 | +6 | $838 | $4,629,996 | 5 | Pyramide Distribution | false | false |
| 16 | 11 | Harry Potter and the Half-Blood Prince | $247,383 | -44.5% | 264 | -128 | $937 | $53,459,592 | 9 | Warner Bros. | false | false |
