| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | My Bloody Valentine | $75,718 | - | 1 | - | $75,718 | $240,882 | 2 | N/A | false | false |
| 2 | - | Tinker Bell and the Lost Treasure | $59,055 | - | 15 | - | $3,937 | $59,055 | 1 | Walt Disney Pictures | true | false |
| 3 | 1 | G-Force | $42,558 | -29.1% | 47 | -1 | $905 | $1,414,793 | 6 | Walt Disney Pictures | false | false |
| 4 | 2 | The Taking of Pelham 123 | $31,342 | -35.6% | 23 | - | $1,362 | $109,916 | 2 | Sony Pictures Releasing | false | false |
| 5 | 4 | The Hangover | $23,654 | -22.1% | 15 | - | $1,576 | $137,968 | 3 | - | false | false |
| 6 | 5 | G.I. Joe: The Rise of Cobra | $18,889 | -36.2% | 26 | - | $726 | $595,778 | 5 | United International Pictures | false | false |
| 7 | - | State of Play | $18,144 | - | 15 | - | $1,209 | $18,144 | 1 | United International Pictures | true | false |
| 8 | 3 | The Accidental Husband | $18,051 | -46.1% | 25 | - | $722 | $147,380 | 3 | Walt Disney Pictures | false | false |
| 9 | - | Knowing | $16,799 | - | 22 | - | $763 | $130,551 | 3 | N/A | false | false |
| 10 | 6 | The Unborn | $8,319 | -54.1% | 21 | - | $396 | $198,769 | 4 | United International Pictures | false | false |
| 11 | 7 | Public Enemies | $4,662 | -66.9% | 15 | - | $310 | $67,786 | 3 | United International Pictures | false | false |
| 12 | 8 | Harry Potter and the Half-Blood Prince | $3,110 | -52.1% | 27 | -6 | $115 | $1,189,812 | 8 | - | false | false |
| 13 | 10 | The Proposal | $2,785 | -12.5% | 4 | -2 | $696 | $302,854 | 9 | Walt Disney Pictures | false | false |
| 14 | 11 | The Time Traveler's Wife | $2,133 | -24% | 8 | - | $266 | $41,781 | 4 | - | false | false |
| 15 | 9 | Ice Age: Dawn of the Dinosaurs | $1,077 | -82.5% | 15 | -7 | $71 | $2,448,394 | 10 | 20th Century Fox International | false | false |
| 16 | 12 | 12 Rounds | $646 | -53% | 7 | -6 | $92 | $32,667 | 4 | 20th Century Fox International | false | false |
