| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | G-Force | $152,698 | -26.6% | 103 | -11 | $1,482 | $2,190,803 | 5 | Walt Disney Pictures | false | false |
| 2 | - | The Ugly Truth | $126,082 | - | 40 | - | $3,152 | $126,082 | 1 | Sony Pictures Releasing | true | false |
| 3 | 1 | The Hangover | $109,372 | -52.8% | 54 | -4 | $2,025 | $560,968 | 3 | Warner Bros. | false | false |
| 4 | 4 | Orphan | $92,624 | -11.9% | 56 | -5 | $1,654 | $246,301 | 2 | Warner Bros. | false | false |
| 5 | 3 | Public Enemies | $90,955 | -22.3% | 45 | - | $2,021 | $255,637 | 2 | United International Pictures | false | false |
| 6 | - | Shorts | $84,812 | - | 43 | - | $1,972 | $84,812 | 1 | Warner Bros. | true | false |
| 7 | 5 | G.I. Joe: The Rise of Cobra | $62,504 | -36.8% | 82 | -4 | $762 | $864,457 | 4 | United International Pictures | false | false |
| 8 | 7 | My Bloody Valentine | $44,854 | -12.2% | 33 | +1 | $1,359 | $253,032 | 3 | Cine Colombia | false | false |
| 9 | 6 | Ice Age: Dawn of the Dinosaurs | $43,039 | -37.5% | 76 | -23 | $566 | $7,915,757 | 9 | 20th Century Fox International | false | false |
| 10 | 8 | The Proposal | $18,301 | -16.9% | 21 | -7 | $871 | $831,286 | 8 | Walt Disney Pictures | false | false |
| 11 | 12 | State of Play | $13,499 | +39.8% | 23 | +8 | $586 | $168,448 | 5 | United International Pictures | false | false |
| 12 | 9 | Harry Potter and the Half-Blood Prince | $9,900 | -54.2% | 17 | -25 | $582 | $2,899,998 | 7 | Warner Bros. | false | false |
| 13 | - | Swing Vote | $9,722 | - | 20 | - | $486 | $9,722 | 1 | Cine Colombia | true | false |
| 14 | 10 | The Bank Job | $7,781 | -39.8% | 17 | -13 | $457 | $180,626 | 5 | Cine Colombia | false | false |
| 15 | 11 | He's Just Not That Into You | $6,360 | -43% | 7 | -3 | $908 | $197,062 | 6 | Cine Colombia | false | false |
| 16 | 15 | Paris | $5,423 | +11.4% | 5 | -2 | $1,084 | $44,381 | 4 | Babilla Ciné | false | false |
| 17 | - | Transporter 3 | $2,713 | - | 4 | - | $678 | $296,104 | 12 | Cineplex | false | false |
| 18 | 16 | The Edge of Heaven | $2,511 | -21.3% | 3 | -1 | $837 | $52,925 | 5 | Cine Colombia | false | false |
| 19 | 17 | Transformers: Revenge of the Fallen | $1,914 | -32.7% | 2 | -4 | $957 | $2,939,275 | 10 | United International Pictures | false | false |
| 20 | 13 | Push | $1,731 | -74.3% | 9 | -2 | $192 | $10,755 | 2 | Cine Colombia | false | false |
