| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | G-Force | $317,863 | - | 68 | - | $4,674 | $317,863 | 1 | Walt Disney Pictures | true | false |
| 2 | - | Inglourious Basterds | $194,008 | - | 45 | - | $4,311 | $194,008 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 2 | District 9 | $71,670 | -70.6% | 56 | -3 | $1,279 | $390,727 | 2 | Sony Pictures Releasing | false | false |
| 4 | 3 | G.I. Joe: The Rise of Cobra | $20,776 | -72.5% | 75 | -5 | $277 | $450,754 | 3 | Paramount Pictures International | false | false |
| 5 | 4 | Ghosts of Girlfriends Past | $9,821 | -66.4% | 31 | -12 | $316 | $383,015 | 4 | Warner Bros. | false | false |
| 6 | 5 | Harry Potter and the Half-Blood Prince | $6,557 | -67.4% | 29 | -25 | $226 | $1,751,577 | 6 | Warner Bros. | false | false |
| 7 | 7 | Public Enemies | $6,163 | -54.4% | 28 | -18 | $220 | $671,622 | 5 | Universal Pictures International (UPI) | false | false |
| 8 | 6 | Ice Age: Dawn of the Dinosaurs | $3,082 | -82.5% | 19 | -13 | $162 | $2,780,134 | 8 | 20th Century Fox International | false | false |
| 9 | 9 | The Hangover | $2,567 | +19.1% | 2 | -1 | $1,283 | $850,195 | 11 | Warner Bros. | false | false |
| 10 | 8 | The Proposal | $1,813 | -83% | 8 | -35 | $226 | $927,675 | 7 | Walt Disney Pictures | false | false |
| 11 | 11 | Fighting | $554 | -14.6% | 5 | +2 | $110 | $99,982 | 7 | Universal Pictures International (UPI) | false | false |
| 12 | 10 | Up | $381 | -80.4% | 5 | -4 | $76 | $614,009 | 10 | Walt Disney Pictures | false | false |
