| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 3 | The Hangover | $231,930 | +54.1% | 58 | -3 | $3,998 | $396,628 | 2 | Warner Bros. | false | false |
| 2 | 1 | G-Force | $208,102 | -27.5% | 114 | -1 | $1,825 | $1,990,538 | 4 | Walt Disney Pictures | false | false |
| 3 | - | Public Enemies | $117,114 | - | 45 | - | $2,602 | $117,114 | 1 | United International Pictures | true | false |
| 4 | - | Orphan | $105,184 | - | 61 | - | $1,724 | $105,184 | 1 | Warner Bros. | true | false |
| 5 | 2 | G.I. Joe: The Rise of Cobra | $98,899 | -38.3% | 86 | +1 | $1,149 | $767,133 | 3 | United International Pictures | false | false |
| 6 | 4 | Ice Age: Dawn of the Dinosaurs | $68,847 | -36.4% | 99 | -7 | $695 | $7,856,320 | 8 | 20th Century Fox International | false | false |
| 7 | 5 | My Bloody Valentine | $51,064 | -36.6% | 32 | -12 | $1,595 | $187,290 | 2 | Cine Colombia | false | false |
| 8 | 7 | The Proposal | $22,012 | -31.1% | 28 | -10 | $786 | $804,486 | 7 | Walt Disney Pictures | false | false |
| 9 | 6 | Harry Potter and the Half-Blood Prince | $21,638 | -63.4% | 42 | -28 | $515 | $2,882,179 | 6 | Warner Bros. | false | false |
| 10 | 8 | The Bank Job | $12,930 | -15.4% | 30 | +14 | $431 | $166,910 | 4 | Cine Colombia | false | false |
| 11 | 13 | He's Just Not That Into You | $11,150 | +62.9% | 10 | +5 | $1,115 | $186,531 | 5 | Cine Colombia | false | false |
| 12 | 9 | State of Play | $9,658 | -33.1% | 15 | -2 | $643 | $151,088 | 4 | United International Pictures | false | false |
| 13 | - | Push | $6,733 | - | 11 | - | $612 | $6,733 | 1 | Cine Colombia | true | false |
| 14 | 12 | 17 Again | $5,001 | -28.3% | 6 | -2 | $833 | $313,479 | 10 | Cine Colombia | false | false |
| 15 | 10 | Paris | $4,867 | -45.1% | 7 | - | $695 | $36,785 | 3 | Babilla Ciné | false | false |
| 16 | 14 | The Edge of Heaven | $3,189 | -52.1% | 4 | -2 | $797 | $48,824 | 4 | Cine Colombia | false | false |
| 17 | 11 | Transformers: Revenge of the Fallen | $2,842 | -62.5% | 6 | -1 | $473 | $2,935,224 | 9 | United International Pictures | false | false |
| 18 | 16 | The Last House on the Left | $1,818 | -49.9% | 4 | -2 | $454 | $146,248 | 7 | United International Pictures | false | false |
| 19 | 15 | Donkey Xote | $1,488 | -75.4% | 11 | -10 | $135 | $11,469 | 2 | Cine Colombia | false | false |
| 20 | 19 | Elegy | $1,040 | -49.8% | 2 | - | $520 | $86,988 | 7 | Cine Colombia | false | false |
