| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Hangover | $1,030,014 | - | 214 | - | $4,813 | $1,030,014 | 1 | Warner Bros. | true | false |
| 2 | 1 | G-Force | $912,824 | -22.5% | 299 | -5 | $3,052 | $2,469,458 | 2 | Walt Disney Pictures | false | false |
| 3 | 3 | Drag Me to Hell | $348,403 | -33.3% | 191 | -3 | $1,824 | $1,116,391 | 2 | Universal Pictures International (UPI) | false | false |
| 4 | 2 | G.I. Joe: The Rise of Cobra | $339,927 | -43% | 305 | -40 | $1,114 | $2,911,359 | 3 | Paramount Pictures International | false | false |
| 5 | 4 | Brüno | $242,772 | -38.5% | 89 | - | $2,727 | $771,912 | 2 | Sony Pictures Releasing | false | false |
| 6 | 5 | Ice Age: Dawn of the Dinosaurs | $240,094 | -36.7% | 300 | -51 | $800 | $43,957,936 | 8 | 20th Century Fox International | false | false |
| 7 | 7 | The Proposal | $183,222 | -21.5% | 146 | -5 | $1,254 | $6,821,303 | 7 | Walt Disney Pictures | false | false |
| 8 | 8 | The Accidental Husband | $115,032 | -48.1% | 120 | -1 | $958 | $963,645 | 3 | PlayArte Pictures | false | false |
| 9 | 6 | Harry Potter and the Half-Blood Prince | $114,317 | -55.3% | 205 | -215 | $557 | $19,591,512 | 6 | Warner Bros. | false | false |
| 10 | - | Veronika Decides to Die | $90,455 | - | 61 | - | $1,482 | $90,455 | 1 | N/A | true | false |
| 11 | 9 | Time of Peace | $80,035 | -39.3% | 53 | +2 | $1,510 | $265,904 | 2 | N/A | false | false |
| 12 | - | Doomsday | $72,975 | - | 66 | - | $1,105 | $72,975 | 1 | Europa Filmes | true | false |
| 13 | 12 | The Invisible Woman | $59,064 | -10.9% | 91 | +1 | $649 | $11,059,981 | 12 | Warner Bros. | false | false |
| 14 | 11 | The Story of Me | $52,720 | -35.2% | 85 | -10 | $620 | $432,561 | 3 | Warner Bros. | false | false |
| 15 | 10 | Public Enemies | $47,936 | -41.2% | 88 | -16 | $544 | $2,758,167 | 5 | Universal Pictures International (UPI) | false | false |
| 16 | 13 | The Butterfly Effect 3: Revelations | $37,701 | -5.7% | 61 | +3 | $618 | $553,472 | 4 | N/A | false | false |
| 17 | - | The Wave | $25,262 | - | 14 | - | $1,804 | $25,262 | 1 | N/A | true | false |
| 18 | 15 | Adrift | $24,583 | +13.3% | 29 | +11 | $847 | $383,157 | 4 | Universal Pictures International (UPI) | false | false |
| 19 | 20 | Last Chance Harvey | $20,246 | +215.9% | 16 | +3 | $1,265 | $731,105 | 10 | N/A | false | false |
| 20 | - | Giant | $18,428 | - | 7 | - | $2,632 | $18,428 | 1 | N/A | true | false |
| 21 | 25 | The International | $17,007 | +425.2% | 25 | +14 | $680 | $599,504 | 10 | Sony Pictures Releasing | false | false |
| 22 | - | The Milk of Sorrow | $16,090 | - | 19 | - | $846 | $16,090 | 1 | Paris Filmes | true | false |
| 23 | 16 | Mid-August Lunch | $15,271 | -28.8% | 16 | -1 | $954 | $122,206 | 4 | N/A | false | false |
| 24 | 17 | If Nothing Else Works Out | $7,267 | -51.8% | 17 | +2 | $427 | $32,203 | 2 | N/A | false | false |
| 25 | 14 | The Girlfriend Experience | $6,924 | -74% | 16 | -10 | $432 | $46,182 | 2 | Paris Filmes | false | false |
| 26 | 19 | Halloween | $6,278 | -20.1% | 43 | -1 | $146 | $753,170 | 5 | PlayArte Pictures | false | false |
| 27 | 18 | Transformers: Revenge of the Fallen | $5,139 | -56.8% | 24 | -13 | $214 | $9,560,181 | 9 | Paramount Pictures International | false | false |
| 28 | 28 | The Baader Meinhof Complex | $4,925 | +129% | 8 | -1 | $615 | $64,149 | 5 | N/A | false | false |
| 29 | 22 | Coração Vagabundo | $4,261 | -0.8% | 8 | - | $532 | $91,617 | 5 | Paramount Pictures International | false | false |
| 30 | 27 | 17 Again | $2,979 | +36% | 21 | +1 | $141 | $1,383,660 | 7 | PlayArte Pictures | false | false |
| 31 | 30 | Hannah Montana: The Movie | $2,107 | +33.4% | 10 | -6 | $210 | $2,731,536 | 11 | Walt Disney Pictures | false | false |
| 32 | 32 | Jean Charles | $998 | +20% | 9 | - | $110 | $1,304,086 | 9 | N/A | false | false |
| 33 | 35 | Angels & Demons | $759 | +338.7% | 3 | +1 | $253 | $13,858,242 | 15 | Sony Pictures Releasing | false | false |
| 34 | 31 | Terminator Salvation | $511 | -58.4% | 4 | -1 | $127 | $6,300,439 | 12 | Sony Pictures Releasing | false | false |
| 35 | 34 | Race to Witch Mountain | $249 | -14.7% | 4 | +1 | $62 | $1,249,852 | 19 | Walt Disney Pictures | false | false |
| 36 | 36 | Waltz with Bashir | $35 | +16.7% | 1 | - | $35 | $110,500 | 21 | Sony Pictures Releasing | false | false |
