| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | G.I. Joe: The Rise of Cobra | $19,867 | - | 5 | - | $3,973 | $35,660 | 1 | United International Pictures | true | false |
| 2 | 2 | The Girl with the Dragon Tattoo | $19,010 | -42.1% | 4 | - | $4,752 | $231,476 | 4 | N/A | false | false |
| 3 | 3 | G-Force | $16,898 | -43.6% | 5 | - | $3,379 | $81,967 | 2 | Walt Disney Pictures | false | false |
| 4 | 1 | Public Enemies | $16,597 | -52.9% | 5 | - | $3,319 | $109,608 | 2 | United International Pictures | false | false |
| 5 | 4 | The Proposal | $15,241 | -48.3% | 6 | - | $2,540 | $169,620 | 3 | Walt Disney Pictures | false | false |
| 6 | 6 | Harry Potter and the Half-Blood Prince | $6,924 | -27.9% | 6 | - | $1,154 | $308,070 | 5 | Warner Bros. | false | false |
| 7 | 5 | Ice Age: Dawn of the Dinosaurs | $4,782 | -54.8% | 8 | -2 | $597 | $252,269 | 7 | 20th Century Fox International | false | false |
| 8 | 8 | My Sister's Keeper | $2,113 | -30.3% | 3 | - | $704 | $83,288 | 6 | N/A | false | false |
| 9 | 7 | Crossing Over | $1,830 | -54.5% | 2 | - | $915 | $10,353 | 2 | Sena | false | false |
| 10 | 11 | Fighting | $1,698 | -14.3% | 2 | - | $849 | $23,915 | 4 | United International Pictures | false | false |
| 11 | 9 | Funny Games | $1,625 | -23.6% | 1 | - | $1,625 | $8,350 | 2 | N/A | false | false |
| 12 | 10 | The Hangover | $1,266 | -37.1% | 1 | -1 | $1,266 | $407,689 | 10 | Warner Bros. | false | false |
| 13 | 14 | The Hurt Locker | $654 | -12.7% | 2 | - | $327 | $26,170 | 6 | N/A | false | false |
| 14 | 13 | Brüno | $611 | -54.5% | 2 | +1 | $305 | $183,046 | 6 | N/A | false | false |
| 15 | 12 | Transformers: Revenge of the Fallen | $200 | -87.1% | 1 | -1 | $200 | $213,912 | 8 | United International Pictures | false | false |
