| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Ugly Truth | $1,902,632 | -31.2% | 284 | +1 | $6,699 | $5,794,035 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | District 9 | $1,807,860 | - | 178 | - | $10,156 | $1,807,860 | 1 | Sony Pictures Releasing | true | false |
| 3 | 2 | G.I. Joe: The Rise of Cobra | $1,251,241 | -46.6% | 223 | - | $5,610 | $4,348,403 | 2 | Paramount Pictures International | false | false |
| 4 | 3 | Harry Potter and the Half-Blood Prince | $886,567 | -34% | 319 | -58 | $2,779 | $31,709,007 | 5 | Warner Bros. | false | false |
| 5 | 5 | My Sister's Keeper | $866,282 | -30.4% | 210 | - | $4,125 | $5,268,516 | 3 | Roadshow Films | false | false |
| 6 | 4 | Public Enemies | $801,108 | -40.2% | 258 | -25 | $3,105 | $6,163,124 | 3 | Universal Pictures International (UPI) | false | false |
| 7 | 6 | Coraline | $752,008 | -18.6% | 212 | - | $3,547 | $2,200,136 | 3 | Trafalgar Releasing | false | false |
| 8 | - | Orphan | $302,689 | - | 110 | - | $2,751 | $302,689 | 1 | Warner Bros. | true | false |
| 9 | - | Bandslam | $266,705 | - | 192 | - | $1,389 | $279,634 | 1 | Hoyts Distribution | true | false |
| 10 | 9 | Beautiful Kate | $198,417 | -13.3% | 29 | - | $6,841 | $594,038 | 3 | Roadshow Films | false | false |
| 11 | - | Balibo | $171,654 | - | 23 | - | $7,463 | $205,479 | 1 | Paramount Pictures International | true | false |
| 12 | 8 | The Hangover | $155,822 | -37.2% | 106 | -35 | $1,470 | $17,571,344 | 10 | Warner Bros. | false | false |
| 13 | 7 | Ice Age: Dawn of the Dinosaurs | $155,786 | -44.9% | 161 | -74 | $967 | $24,550,337 | 7 | 20th Century Fox International | false | false |
| 14 | - | Kaminey | $108,127 | - | 12 | - | $9,010 | $108,127 | 1 | Mind Blowing Films | true | false |
| 15 | 11 | Transformers: Revenge of the Fallen | $83,448 | -54% | 66 | -69 | $1,264 | $33,370,275 | 8 | Paramount Pictures International | false | false |
| 16 | 16 | Coco Before Chanel | $75,615 | -5.9% | 39 | - | $1,938 | $2,015,356 | 8 | Roadshow Films | false | false |
| 17 | 14 | Chéri | $55,773 | -35.4% | 46 | -9 | $1,212 | $761,243 | 4 | Icon Film Distribution | false | false |
| 18 | 10 | Drag Me to Hell | $45,306 | -76.5% | 50 | -81 | $906 | $2,152,862 | 4 | Roadshow Films | false | false |
| 19 | 15 | My Life in Ruins | $39,169 | -51.6% | 52 | -44 | $753 | $2,189,717 | 5 | 20th Century Fox International | false | false |
| 20 | 12 | The Proposal | $36,919 | -63.8% | 36 | -54 | $1,025 | $13,779,505 | 9 | Walt Disney Pictures | false | false |
| 21 | - | Eden Is West | $7,674 | - | 11 | - | $697 | $7,674 | - | Jump Street Films | - | false |
| 22 | - | The Cove | $6,673 | - | 10 | - | $667 | $6,673 | - | Gil Scrine Films | - | false |
| 23 | - | Every Little Step | $1,878 | - | 3 | - | $626 | $98,243 | 7 | Sony Pictures Releasing | false | false |
| 24 | - | Subdivision | $1,389 | - | 21 | - | $66 | $1,389 | - | Walt Disney Pictures | - | false |
